ArticleInfection and immunity2000
Yersinia pestis YscG protein is a Syc-like chaperone that directly binds yscE.
Article in Infection and immunity, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 39 citations in OpenAlex.
- Bcr4 Is a Chaperone for the Inner Rod Protein in theMicrobiology spectrum · 2022Article
- Article
- Chaperone-mediated secretion switching from early to middle substrates in the type III secretion system encoded byThe Journal of biological chemistry · 2019Article
- The YscE/YscG chaperone and YscF N-terminal sequences target YscF to the Yersinia pestis type III secretion apparatus.Microbiology (Reading, England) · 2018Article
- Protein export according to schedule: architecture, assembly, and regulation of type III secretion systems from plant- and animal-pathogenic bacteria.Microbiology and molecular biology reviews : MMBR · 2012Review
- Functional characterization of SsaE, a novel chaperone protein of the type III secretion system encoded by Salmonella pathogenicity island 2.Journal of bacteriology · 2009Article
- Structure of AscE and induced burial regions in AscE and AscG upon formation of the chaperone needle-subunit complex of type III secretion system in Aeromonas hydrophila.Protein science : a publication of the Protein Society · 2008Article
- Structural characterization of the Yersinia pestis type III secretion system needle protein YscF in complex with its heterodimeric chaperone YscE/YscG.Journal of molecular biology · 2008Article
- Bioinformatic and biochemical evidence for the identification of the type III secretion system needle protein of Chlamydia trachomatis.Journal of bacteriology · 2008Article
- Structure of the heterotrimeric complex that regulates type III secretion needle formation.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Molecular model of a type III secretion system needle: Implications for host-cell sensing.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Quorum sensing affects virulence-associated proteins F1, LcrV, KatY and pH6 etc. of Yersinia pestis as revealed by protein microarray-based antibody profiling.Microbes and infection · 2006Article
- Bioinformatics analysis of the locus for enterocyte effacement provides novel insights into type-III secretion.BMC microbiology · 2005Article
- Process of protein transport by the type III secretion system.Microbiology and molecular biology reviews : MMBR · 2004Review
- Type III secretion system genes in clinical Aeromonas isolates.Journal of clinical microbiology · 2004Article
- InvB is required for type III-dependent secretion of SopA in Salmonella enterica serovar Typhimurium.Journal of bacteriology · 2004Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Pathogenic Yersinia species secrete virulence proteins, termed Yersinia outer proteins (Yops), upon contact with a eukaryotic cell. The secretion machinery is composed of 21 Yersinia secretion (Ysc) proteins. Yersinia pestis mutants defective in expression of YscG or YscE were unable to export the Yops. YscG showed structural and limited amino-acid-sequence similarities to members of the specific Yop chaperone (Syc) family of proteins. YscG specifically recognized and bound YscE; however, unlike previously characterized Syc substrates, YscE was not exported from the cell. These data suggest that YscG functions as a chaperone for YscE.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.