ArticleTransgenic research2000
Adaptation of Spodoptera exigua (Lepidoptera: Noctuidae) to barley trypsin inhibitor BTI-CMe expressed in transgenic tobacco.
Article in Transgenic research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 58 citations in OpenAlex.
- A constitutive serine protease inhibitor suppresses herbivore performance in tea (Horticulture research · 2023Article
- Transcription and Activity of Digestive Enzymes ofFrontiers in physiology · 2019Article
- Interactive Responses ofInternational journal of molecular sciences · 2018Article
- Arabidopsis Kunitz Trypsin Inhibitors in Defense Against Spider Mites.Frontiers in plant science · 2018Article
- Serine peptidase inhibitor Kazal type 1 (SPINK1) as novel downstream effector of the cadherin-17/β-catenin axis in hepatocellular carcinoma.Cellular oncology (Dordrecht, Netherlands) · 2017Article
- Phytocystatins: Defense Proteins against Phytophagous Insects and Acari.International journal of molecular sciences · 2016Review
- Transcriptional Analysis of The Adaptive Digestive System of The Migratory Locust in Response to Plant Defensive Protease Inhibitors.Scientific reports · 2016Article
- Article
- Inhibitory properties of cysteine protease pro-peptides from barley confer resistance to spider mite feeding.PloS one · 2015Article
- DELLA proteins modulate Arabidopsis defences induced in response to caterpillar herbivory.Journal of experimental botany · 2014Article
- Article
- Expression of a nematode symbiotic bacterium-derived protease inhibitor protein in tobacco enhanced tolerance against Myzus persicae.Plant cell reports · 2012Article
- Microbial and fungal protease inhibitors--current and potential applications.Applied microbiology and biotechnology · 2012Review
- Gene pyramiding of peptidase inhibitors enhances plant resistance to the spider mite Tetranychus urticae.PloS one · 2012Article
- Expression of a barley cystatin gene in maize enhances resistance against phytophagous mites by altering their cysteine-proteases.Plant cell reports · 2011Article
- Potential use of a serpin from Arabidopsis for pest control.PloS one · 2011Article
- Caterpillar saliva interferes with induced Arabidopsis thaliana defence responses via the systemic acquired resistance pathway.Journal of experimental botany · 2008Article
- Effects of potato plants expressing a barley cystatin on the predatory bug Podisus maculiventris via herbivorous prey feeding on the plant.Transgenic research · 2007Article
- Structural and functional diversities in lepidopteran serine proteases.Cellular & molecular biology letters · 2006Review
- Molecular cloning and expression of an alpha-amylase inhibitor from rye with potential for controlling insect pests.The protein journal · 2005Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nicotiana tabacum plants were transformed with the cDNA of barley trypsin inhibitor BTI-CMe under the control of the 35S CaMV promoter. Although the transgene was expressed and the protein was active in the homozygous lines selected, growth of Spodoptera exigua (Lepidoptera: Noctuidae) larvae reared on transgenic plants was not affected. The protease activity in larval midgut extracts after 2 days feeding on transformed tobacco leaves from the highest expressing plant showed a reduction of 25% in the trypsin-like activity compared to that from insects fed on non-transformed controls. The susceptibility of digestive serine-proteases to inhibition by BTI-CMe was confirmed by activity staining gels. This decrease was compensated with a significant induction of leucine aminopeptidase-like and carboxipeptidase A-like activities, while chymotrypsin-, elastase-, and carboxipeptidase B-like proteases were not affected.
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