ArticleChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2000
Common methylation characteristics of sex chromosomes in somatic and germ cells from mouse, lemur and human.
Article in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 41 citations in OpenAlex.
- Article
- The influence of DNA methylation on monoallelic expression.Essays in biochemistry · 2019Review
- Infrared nanospectroscopic mapping of a single metaphase chromosome.Nucleic acids research · 2019Article
- Characterization of whole-genome autosomal differences of DNA methylation between men and women.Epigenetics & chromatin · 2015Article
- Global DNA Methylation patterns on marsupial and devil facial tumour chromosomes.Molecular cytogenetics · 2015Article
- Article
- Chromosome-wide regulation of euchromatin-specific 5mC to 5hmC conversion in mouse ES cells and female human somatic cells.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2012Article
- Smchd1-dependent and -independent pathways determine developmental dynamics of CpG island methylation on the inactive X chromosome.Developmental cell · 2012Article
- Comparative cytogenetic study on two species of the genus Entedon Dalman, 1820 (Hymenoptera, Eulophidae) using DNA-binding fluorochromes and molecular and immunofluorescent markers.Comparative cytogenetics · 2012Article
- Role of ATRX in chromatin structure and function: implications for chromosome instability and human disease.Reproduction (Cambridge, England) · 2011Review
- Epigenetic modifications on X chromosomes in marsupial and monotreme mammals and implications for evolution of dosage compensation.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Histone methylation marks play important roles in predicting the methylation status of CpG islands.Biochemical and biophysical research communications · 2008Article
- Association of ATRX with pericentric heterochromatin and the Y chromosome of neonatal mouse spermatogonia.BMC molecular biology · 2008Article
- Article
- Comparative isoschizomer profiling of cytosine methylation: the HELP assay.Genome research · 2006Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA methylation of sex chromosomes was analysed using anti-5-methylcytosine antibodies on metaphase chromosomes of somatic cells from three species: human, lemur and mouse. Germ cells were also studied in male mouse. In female cells (human and mouse), the late replicating X was always the less methylated chromosome. Compared with autosomes, the methylation of both X chromosomes was always lower in fibroblasts than in lymphocytes and the difference was always greater in mouse than in human. In human, mouse and lemur male cells, the labelling of the unique X chromosome was quite similar to that of the early replicating X from female cells. Except for the heterochromatic region of the human Y chromosome, strongly methylated, the overall methylation of the Y chromosome was low. In mouse testicular cells, a variety of DNA methylation patterns was observed according to the cell type and the state of differentiation. Finally, the only structures of sex chromosomes which remain methylated in all conditions correspond to their pseudoautosomal regions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.