ArticleNucleic acids research2000
Hammerhead-mediated processing of satellite pDo500 family transcripts from Dolichopoda cave crickets.
Article in Nucleic acids research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
38 citing papers in PubMed, 83 citations in OpenAlex.
- A Singular and Widespread Group of Mobile Genetic Elements: RNA Circles with Autocatalytic Ribozymes.Cells · 2020Review
- Small circRNAs with self-cleaving ribozymes are highly expressed in diverse metazoan transcriptomes.Nucleic acids research · 2020Article
- Satellite DNAs are conserved and differentially transcribed among Gryllus cricket species.DNA research : an international journal for rapid publication of reports on genes and genomes · 2018Article
- Centromere and Pericentromere Transcription: Roles and Regulation … in Sickness and in Health.Frontiers in genetics · 2018Review
- Numerous small hammerhead ribozyme variants associated with Penelope-like retrotransposons cleave RNA as dimers.RNA biology · 2017Article
- Circular RNAs with hammerhead ribozymes encoded in eukaryotic genomes: The enemy at home.RNA biology · 2017Article
- The Hammerhead Ribozyme: A Long History for a Short RNA.Molecules (Basel, Switzerland) · 2017Review
- Retrozymes are a unique family of non-autonomous retrotransposons with hammerhead ribozymes that propagate in plants through circular RNAs.Genome biology · 2016Article
- RNA motif search with data-driven element ordering.BMC bioinformatics · 2016Article
- Chemistry and Biology of Self-Cleaving Ribozymes.Trends in biochemical sciences · 2015Review
- Is radon emission in caves causing deletions in satellite DNA sequences of cave-dwelling crickets?PloS one · 2015Article
- Synergism and mutualism in non-enzymatic RNA polymerization.Life (Basel, Switzerland) · 2014Review
- Eukaryotic penelope-like retroelements encode hammerhead ribozyme motifs.Molecular biology and evolution · 2014Article
- G17-modified hammerhead ribozymes are active in vitro and in vivo.RNA (New York, N.Y.) · 2013Article
- The ubiquitous hammerhead ribozyme.RNA (New York, N.Y.) · 2012Review
- Processing and translation initiation of non-long terminal repeat retrotransposons by hepatitis delta virus (HDV)-like self-cleaving ribozymes.The Journal of biological chemistry · 2011Article
- Identification of hammerhead ribozymes in all domains of life reveals novel structural variations.PLoS computational biology · 2011Article
- Structure-based search reveals hammerhead ribozymes in the human microbiome.The Journal of biological chemistry · 2011Article
- From alpaca to zebrafish: hammerhead ribozymes wherever you look.RNA (New York, N.Y.) · 2011Article
- Ubiquitous presence of the hammerhead ribozyme motif along the tree of life.RNA (New York, N.Y.) · 2010Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This work reports the discovery and functional characterization of catalytically active hammerhead motifs within satellite DNA of the pDo500 family from several DOLICHOPODA: cave cricket species. We show that in vitro transcribed RNA of some members of this satellite DNA family do self-cleave in vitro. This self-cleavage activity is correlated with the efficient in vivo processing of long primary transcripts into monomer-sized RNA. The high sequence conservation of the satellite pDo500 DNA family among genetically isolated DOLICHOPODA: schiavazzii populations, as well as other DOLICHOPODA: species, along with the fact that satellite members are actively transcribed in vivo suggests that the hammerhead-encoding satellite transcripts are under selective pressure, perhaps because they fulfil an important physiological role or function. Remarkably, this is the third example of hammerhead ribozyme structures associated with transcribed repetitive DNA sequences from animals. The possibility that such an association may not be purely coincidental is discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.