Evidence map›Paper›PMID 11024156›Full record

ArticleJournal of virology2000

HLA class I-restricted cytotoxic T-cell epitopes of the respiratory syncytial virus fusion protein.

A H Brandenburg, L de Waal, H H Timmerman, P Hoogerhout, R L de Swart, A D Osterhaus

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Identification of a DRB3*011:01-restricted CD4Frontiers in immunology · 2023
    Article
  3. Review
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  6. Human Respiratory Syncytial Virus: Infection and Pathology.Seminars in respiratory and critical care medicine · 2016
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

A H BrandenburgInstitute of Virology, Erasmus University Hospital, 3000 DR Rotterdam, The Netherlands.
L de Waal
H H Timmerman
P Hoogerhout
R L de Swart
A D Osterhaus
Erasmus University Rotterdam · NLInstitute of Virology of the Slovak Academy of Sciences · SKNational Institute for Public Health and the Environment · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virus-specific cytotoxic T lymphocytes (CTL) play a major role in the clearance of respiratory syncytial virus (RSV) infection. We have generated cytotoxic T-cell clones (TCC) from two infants who had just recovered from severe RSV infection. These TCC were functionally characterized and used to identify HLA class I (B57 and C12)-restricted CTL epitopes of RSV.

Indexed as

Epitope MappingEpitopes, T-LymphocyteHistocompatibility Antigens Class IHumansInfantInfant, NewbornRespiratory Syncytial VirusesRespiratory Syncytial Virus InfectionsT-Lymphocytes, CytotoxicViral Fusion ProteinsViral ProteinsEpitopes, T-LymphocyteHistocompatibility Antigens Class IViral Fusion ProteinsViral Proteins

Identifiers

PMID11024156
PMCPMC102066
OpenAlexW2123834730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.