ReviewVirus genes2000
Iridovirus homologues of cellular genes--implications for the molecular evolution of large DNA viruses.
Review in Virus genes, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 39 citations in OpenAlex.
- Downregulation of the host ribonucleotide reductase subunit M2 via the Wnt/β-catenin pathway is a novel mechanism for duck plague virus replication and a potential antiviral target.Poultry science · 2026Article
- Genome analysis of Ranavirus frog virus 3 isolated from American Bullfrog (Lithobates catesbeianus) in South America.Scientific reports · 2019Article
- Coevolution of hytrosaviruses and host immune responses.BMC microbiology · 2018Review
- The End of a 60-year Riddle: Identification and Genomic Characterization of an Iridovirus, the Causative Agent of White Fat Cell Disease in Zooplankton.G3 (Bethesda, Md.) · 2018Article
- Article
- Evolution of viruses and cells: do we need a fourth domain of life to explain the origin of eukaryotes?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015Article
- Recent host-shifts in ranaviruses: signatures of positive selection in the viral genome.The Journal of general virology · 2013Article
- Review
- Virome profiling of bats from Myanmar by metagenomic analysis of tissue samples reveals more novel Mammalian viruses.PloS one · 2013Article
- Megalocytiviruses.Viruses · 2012Review
- Fosmid library end sequencing reveals a rarely known genome structure of marine shrimp Penaeus monodon.BMC genomics · 2011Article
- Vaccinia virus-encoded ribonucleotide reductase subunits are differentially required for replication and pathogenesis.PLoS pathogens · 2010Article
- Whole-proteome phylogeny of large dsDNA viruses and parvoviruses through a composition vector method related to dynamical language model.BMC evolutionary biology · 2010Article
- Rana grylio virus thymidine kinase gene: an early gene of iridovirus encoding for a cytoplasmic protein.Virus genes · 2009Article
- Genome analysis of a Glossina pallidipes salivary gland hypertrophy virus reveals a novel, large, double-stranded circular DNA virus.Journal of virology · 2008Article
- Whole genome molecular phylogeny of large dsDNA viruses using composition vector method.BMC evolutionary biology · 2007Article
- Complete genome sequence of the grouper iridovirus and comparison of genomic organization with those of other iridoviruses.Journal of virology · 2005Article
- Molecular anatomy of Chilo iridescent virus genome and the evolution of viral genes.Virus genes · 2002Article
- Common origin of four diverse families of large eukaryotic DNA viruses.Journal of virology · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iridoviruses belong to the group of large cytoplasmic deoxyriboviruses and infect either insects or vertebrates. In analogy to other large DNA viruses of eucaryotes it was found that iridoviruses encode a number of cellular protein homologues. The majority of these proteins represent orthologues of cellular enzymes involved in transcription, replication, and nucleotide metabolism. Others may have the potential to interfere with cell cycle regulation or immune defence mechanisms of the host. This raises the question about the phylogenetic origin of the corresponding viral genes. During the evolution of large cytoplasmic DNA viruses such as iridoviruses, poxviruses, and African swine fever virus the acquirement of cellular genes appears to be a crucial event. Each member of this group of viruses encodes a DNA polymerase, two subunits of the DNA-dependent RNA polymerase, and two subunits of the ribonucleotide reductase. It is important to note that all of these viral proteins show a high level of multidomain structure conservation as compared to their cellular orthologues. As a consequence the large cytoplasmic DNAviruses have the ability to replicate independently of the cellular nucleus in the cytoplasm of the infected cell. Assuming a common cellular origin of viral DNA polymerase genes the corresponding amino acid sequences were chosen to construct a phylogenetic tree showing the relatedness among large DNA viruses of eucaryotes.
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11022791W1496258651What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.