ArticleBone marrow transplantation2000
Utility of obtaining blood cultures in febrile neutropenic patients undergoing bone marrow transplantation.
Article in Bone marrow transplantation, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 64 citations in OpenAlex.
- Diagnostic Yield of Repeat Blood Cultures and Risk Factors for Bloodstream Infection in Persistent Febrile Neutropenia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- Blood culture utilization and impact of stewardship practices during a national blood culture bottle shortage at a cancer center.Journal of clinical microbiology · 2026Article
- Changing the culture of blood cultures: Opportunities for diagnostic stewardship in febrile neutropenia.Transplant infectious disease : an official journal of the Transplantation Society · 2024Article
- Reducing Repeat Blood Cultures in Febrile Neutropenia: A Single-Center Experience.Open forum infectious diseases · 2022Article
- Timing of Blood Cultures in the Setting of Febrile Neutropenia: An Australian Institutional ExperienceTurkish journal of haematology : official journal of Turkish Society of Haematology · 2021Article
- Plasma Cell-Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients.Open forum infectious diseases · 2018Article
- Susceptible period for cardiovascular complications in patients recovering from sepsis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2018Article
- Epidemiology of infections following haploidentical peripheral blood hematopoietic cell transplantation.Transplant infectious disease : an official journal of the Transplantation Society · 2017Article
- Rates of Microbiologically Diagnosed Infection and Pathogen Detection in Hematopoietic Stem Cell Transplant Patients.Military medicine · 2016Article
- Repeat blood cultures in children with persistent fever and neutropenia: Diagnostic and clinical implications.Pediatric blood & cancer · 2015Article
- Melting Temperature Mapping Method: A Novel Method for Rapid Identification of Unknown Pathogenic Microorganisms within Three Hours of Sample Collection.Scientific reports · 2015Article
- Utility of surveillance blood cultures in patients undergoing hematopoietic stem cell transplantation.Antimicrobial resistance and infection control · 2014Article
- Repeating blood cultures in neutropenic children with persistent fevers when the initial blood culture is negative.Pediatric blood & cancer · 2013Article
- Diagnostic value of PCR analysis of bacteria and fungi from blood in empiric-therapy-resistant febrile neutropenia.Journal of clinical microbiology · 2010Article
- Utility of a commercially available multiplex real-time PCR assay to detect bacterial and fungal pathogens in febrile neutropenia.Journal of clinical microbiology · 2009Article
- Assessment of an alternative meropenem dosing strategy compared with imipenem-cilastatin or traditional meropenem dosing after cefepime failure or intolerance in adults with neutropenic fever.Pharmacotherapy · 2009Article
- Bench-to-bedside review: the promise of rapid infection diagnosis during sepsis using polymerase chain reaction-based pathogen detection.Critical care (London, England) · 2009Review
- [Molecular biological detection of pathogens in patients with sepsis. Potentials, limitations and perspectives].Der Anaesthesist · 2008Review
- Value of surveillance blood culture for early diagnosis of occult bacteremia in patients on corticosteroid therapy following allogeneic hematopoietic stem cell transplantation.Bone marrow transplantation · 2005Article
- Bacteremia after hematopoietic stem cell transplantation: incidence and predictive value of surveillance cultures.Bone marrow transplantation · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
Abstract
Infection remains an important cause of morbidity and mortality after bone marrow or stem cell transplantation. To evaluate the role of obtaining blood cultures for intermittent or persistent fever in neutropenic patients on antibiotic therapy, we performed a retrospective chart review of 196 consecutive patients admitted to the Bone Marrow Transplant Unit at the University of North Carolina Hospitals from 1995 to 1998. From the cohort of 196 patients, 154 patients developed neutropenic fever. The initial blood culture was positive in 16 of 145 patients during the first fever episode giving a prevalence of 11%. From the total of 109 patients that had blood cultures drawn after day 1 of fever, five patients had blood cultures positive for a pathogen, a prevalence of 4.6%. In only one patient, did blood cultures drawn after day 1 identify an organism not present on day 1 (prevalence 0.9%). After reviewing the results in the first 105 patients, we changed our timing of collection of blood cultures. Forty-nine patients were treated in this manner and we found that the mean number of blood cultures decreased from 9.2 to 4.7 per patient without a change in the frequency of infectious complications or length of hospitalization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.