ArticleThe Plant cell2000
Four genes of Medicago truncatula controlling components of a nod factor transduction pathway.
Article in The Plant cell, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 199 papers.
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Who cites it
199 citing papers in PubMed, 538 citations in OpenAlex.
- Review
- Nissolia brasiliensis as a nonnodulating model legume.Plant physiology · 2026Article
- An NSP2-MYB module orchestrates flavonoid biosynthesis and nodule symbiosis.Current biology : CB · 2026Article
- Pangenome analysis provides insights into legume evolution and breeding.Nature genetics · 2025Article
- A plant Lysin Motif Receptor-Like Kinase plays an ancestral function in mycorrhiza.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
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- Conservation of symbiotic signaling since the most recent common ancestor of land plants.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
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- A receptor required for chitin perception facilitates arbuscular mycorrhizal associations and distinguishes root symbiosis from immunity.Current biology : CB · 2024Article
- A rare non-canonical splice site in Trema orientalis SYMRK does not affect its dual symbiotic functioning in endomycorrhiza and rhizobium nodulation.BMC plant biology · 2023Article
- Single-cell analysis identifies genes facilitating rhizobium infection in Lotus japonicus.Nature communications · 2023Article
- Comparative phylotranscriptomics reveals ancestral and derived root nodule symbiosis programmes.Nature plants · 2023Article
- Sucrose-induced auxin conjugate hydrolase restores symbiosis in a Medicago cytokinin perception mutant.Plant physiology · 2023Article
- A modified aeroponic system for growing small-seeded legumes and other plants to study root systems.Plant methods · 2023Article
- The putative transporter MtUMAMIT14 participates in nodule formation in Medicago truncatula.Scientific reports · 2023Article
- Temporal change in chromatin accessibility predicts regulators of nodulation in Medicago truncatula.BMC biology · 2022Article
- Nutrient regulation of lipochitooligosaccharide recognition in plants via NSP1 and NSP2.Nature communications · 2022Article
- Right time, right place: The dynamic role of hormones in rhizobial infection and nodulation of legumes.Plant communications · 2022Review
- Visualization of the Crossroads between a Nascent Infection Thread and the First Cell Division Event inInternational journal of molecular sciences · 2022Article
139 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rhizobium nodulation (Nod) factors are lipo-chitooligosaccharides that act as symbiotic signals, eliciting several key developmental responses in the roots of legume hosts. Using nodulation-defective mutants of Medicago truncatula, we have started to dissect the genetic control of Nod factor transduction. Mutants in four genes (DMI1, DMI2, DMI3, and NSP) were pleiotropically affected in Nod factor responses, indicating that these genes are required for a Nod factor-activated signal transduction pathway that leads to symbiotic responses such as root hair deformations, expressions of nodulin genes, and cortical cell divisions. Mutant analysis also provides evidence that Nod factors have a dual effect on the growth of root hair: inhibition of endogenous (plant) tip growth, and elicitation of a novel tip growth dependent on (bacterial) Nod factors. dmi1, dmi2, and dmi3 mutants are also unable to establish a symbiotic association with endomycorrhizal fungi, indicating that there are at least three common steps to nodulation and endomycorrhization in M. truncatula and providing further evidence for a common signaling pathway between nodulation and mycorrhization.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.