ReviewEmerging infectious diseases
Using DNA microarrays to study host-microbe interactions.
Review in Emerging infectious diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed.
- The Slr protein of Streptococcus pyogenes is selectively expressed in vivo and is a target for protective antibodies.EMBO molecular medicine · 2026Article
- Review
- Neighborhood-based inference and restricted Boltzmann machine for microbe and drug associations prediction.PeerJ · 2022Article
- Use of gene expression studies to investigate the human immunological response to malaria infection.Malaria journal · 2019Review
- Twenty years of bacterial genome sequencing.Nature reviews. Microbiology · 2015Review
- Transcriptome Profiles of Human Lung Epithelial Cells A549 Interacting with Aspergillus fumigatus by RNA-Seq.PloS one · 2015Article
- Gene expression profile in human skeletal muscle cells infected with human adenovirus type 36.Journal of medical virology · 2012Article
- Ebola virion attachment and entry into human macrophages profoundly effects early cellular gene expression.PLoS neglected tropical diseases · 2011Article
- A sensitive high-throughput assay for evaluating host-pathogen interactions in Cryptococcus neoformans infection.PloS one · 2011Article
- Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila.Frontiers in microbiology · 2011Article
- Functional genomics of human bronchial epithelial cells directly interacting with conidia of Aspergillus fumigatus.BMC genomics · 2010Article
- Searching for the elusive typhoid diagnostic.BMC infectious diseases · 2010Review
- Intravaginal immunization of mice with recombinant Salmonella enterica serovar Typhimurium expressing human papillomavirus type 16 antigens as a potential route of vaccination against cervical cancer.Infection and immunity · 2008Article
- Beyond good and evil in the oral cavity: insights into host-microbe relationships derived from transcriptional profiling of gingival cells.Journal of dental research · 2008Review
- Animal models: an important tool in mycology.Medical mycology · 2007Review
- Transcriptional profile of red seabream iridovirus in a fish model as revealed by viral DNA microarrays.Virus genes · 2007Article
- Leishmania major abrogates gamma interferon-induced gene expression in human macrophages from a global perspective.Infection and immunity · 2007Article
- Gingival epithelial cell transcriptional responses to commensal and opportunistic oral microbial species.Infection and immunity · 2007Article
- Molecular characterisation of the early response in pigs to experimental infection with Actinobacillus pleuropneumoniae using cDNA microarrays.Acta veterinaria Scandinavica · 2007Article
- Computer simulation study of molecular recognition in model DNA microarrays.Biophysical journal · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Complete genomic sequences of microbial pathogens and hosts offer sophisticated new strategies for studying host-pathogen interactions. DNA microarrays exploit primary sequence data to measure transcript levels and detect sequence polymorphisms, for every gene, simultaneously. The design and construction of a DNA microarray for any given microbial genome are straightforward. By monitoring microbial gene expression, one can predict the functions of uncharacterized genes, probe the physiologic adaptations made under various environmental conditions, identify virulence-associated genes, and test the effects of drugs. Similarly, by using host gene microarrays, one can explore host response at the level of gene expression and provide a molecular description of the events that follow infection. Host profiling might also identify gene expression signatures unique for each pathogen, thus providing a novel tool for diagnosis, prognosis, and clinical management of infectious disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.