ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2000
Remodeling of membrane properties and dendritic architecture accompanies the postembryonic conversion of a slow into a fast motoneuron.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 67 citations in OpenAlex.
- Inwardly rectifying potassium channels: Critical insights for insect species and Apis mellifera.Channels (Austin, Tex.) · 2025Review
- Single-cell type analysis of wing premotor circuits in the ventral nerve cord ofbioRxiv : the preprint server for biology · 2025Article
- Somato-dendritic decoupling as a novel mechanism for protracted cortical maturation.BMC biology · 2016Article
- A Flight Sensory-Motor to Olfactory Processing Circuit in the Moth Manduca sexta.Frontiers in neural circuits · 2016Article
- Modeling the Influence of Ion Channels on Neuron Dynamics in Drosophila.Frontiers in computational neuroscience · 2015Article
- Molecular and functional characterization of Anopheles gambiae inward rectifier potassium (Kir1) channels: a novel role in egg production.Insect biochemistry and molecular biology · 2014Article
- Sequential acquisition of cacophony calcium currents, sodium channels and voltage-dependent potassium currents affects spike shape and dendrite growth during postembryonic maturation of an identified Drosophila motoneuron.The European journal of neuroscience · 2014Article
- Putative excitatory and putative inhibitory inputs are localised in different dendritic domains in a Drosophila flight motoneuron.The European journal of neuroscience · 2013Article
- Temporal coherency between receptor expression, neural activity and AP-1-dependent transcription regulates Drosophila motoneuron dendrite development.Development (Cambridge, England) · 2013Article
- Quantification of dendritic and axonal growth after injury to the auditory system of the adult cricket Gryllus bimaculatus.Frontiers in physiology · 2013Article
- Developmental and activity-dependent plasticity of filiform hair receptors in the locust.Frontiers in physiology · 2013Article
- Tiling among stereotyped dendritic branches in an identified Drosophila motoneuron.The Journal of comparative neurology · 2010Article
- Postembryonic development of centrally generated flight motor patterns in the hawkmoth, Manduca sexta.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2010Article
- Shaker and Shal mediate transient calcium-independent potassium current in a Drosophila flight motoneuron.Journal of neurophysiology · 2009Article
- PTX-induced hyperexcitability affects dendritic shape and GABAergic synapse density but not synapse distribution during Manduca postembryonic motoneuron development.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2009Article
- Calcium spikes in a leech nonspiking neuron.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2009Article
- NeuroMorpho.Org implementation of digital neuroscience: dense coverage and integration with the NIF.Neuroinformatics · 2008Article
- Characterization of voltage-dependent Ca2+ currents in identified Drosophila motoneurons in situ.Journal of neurophysiology · 2008Article
- Steroid hormone activation of wandering in the isolated nervous system of Manduca sexta.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2006Article
- Activity affects dendritic shape and synapse elimination during steroid controlled dendritic retraction in Manduca sexta.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The postembryonic acquisition of behavior requires alterations in neuronal circuitry, which ultimately must be understood as specific changes in neuronal structure, membrane properties, and synaptic connectivity. This study addresses this goal by describing the postembryonic remodeling of the excitability and dendritic morphology of an identified motoneuron, MN5, which during the metamorphosis of Manduca sexta (L.) changes from a slow motoneuron that is involved in larval-crawling behavior into a fast adult flight motoneuron. A fivefold lower input resistance, a higher firing threshold, and an increase in voltage-activated K(+) current contribute to a lower excitability of the adult MN5, which is a prerequisite for its newly acquired behavioral role. In addition, the adult MN5 displays larger Ca(2+) currents. The dendrites of MN5 undergo extensive remodeling. Drastic regression of larval dendrites during early pupal stages is followed by rapid growth of new dendrites. Critical changes in excitability take place during the onset of adult dendrite formation. Larval Ca(2+) currents are absent when dendritic remodeling is most dramatic but increase markedly during later development. Changes in Ca(2+) and K(+) currents follow different time courses, allowing the transient occurrence of Ca(2+) spikes during pupal stages when new dendritic branching ceases. The adult MN5 can produce prolonged Ca(2+) spikes after K(+) currents are reduced. We suggest that alterations in Ca(2+) and K(+) currents are necessary for the participation of MN5 in flight behavior and that the transient production of Ca(2+) spikes may influence postembryonic dendritic remodeling.
Indexed as
Identifiers
10995839PMC6772846W1617822148What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.