ArticleThe Journal of cell biology2000
The reduction of chromosome number in meiosis is determined by properties built into the chromosomes.
Article in The Journal of cell biology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 68 citations in OpenAlex.
- Meiosis-specific functions of kinetochore protein SPC105R required for chromosome segregation inMolecular biology of the cell · 2024Article
- Meiosis-specific functions of kinetochore protein SPC105R required for chromosome segregation inbioRxiv : the preprint server for biology · 2024Article
- Chromosome-level assembly ofFrontiers in plant science · 2024Article
- The Four Causes: The Functional Architecture of Centromeres and Kinetochores.Annual review of genetics · 2022Review
- Asynapsis and unreduced gamete formation in a Trifolium interspecific hybrid.BMC plant biology · 2022Article
- Micromanipulation of Chromosomes in Insect Spermatocytes.Journal of visualized experiments : JoVE · 2018Article
- Dynamics and control of sister kinetochore behavior during the meiotic divisions in Drosophila spermatocytes.PLoS genetics · 2018Article
- The chromosomal basis of meiotic acentrosomal spindle assembly and function in oocytes.Chromosoma · 2017Review
- Alterations in chromosomal synapses and DNA repair in apoptotic spermatocytes of Mus m. domesticus.European journal of histochemistry : EJH · 2016Article
- PATRONUS1 is expressed in meiotic prophase I to regulate centromeric cohesion in Arabidopsis and shows synthetic lethality with OSD1.BMC plant biology · 2015Article
- A meiotic mystery: How sister kinetochores avoid being pulled in opposite directions during the first division.BioEssays : news and reviews in molecular, cellular and developmental biology · 2015Article
- Chromosome interaction over a distance in meiosis.Royal Society open science · 2015Review
- From equator to pole: splitting chromosomes in mitosis and meiosis.Genes & development · 2015Review
- Sister kinetochores are mechanically fused during meiosis I in yeast.Science (New York, N.Y.) · 2014Article
- Chromosome segregation in budding yeast: sister chromatid cohesion and related mechanisms.Genetics · 2014Review
- Mechanism of the chromosome-induced polar body extrusion in mouse eggs.Cell division · 2011Article
- Mechanism of haploidy-dependent unreductional meiotic cell division in polyploid wheat.Chromosoma · 2010Article
- High-throughput knockout screen in Schizosaccharomyces pombe identifies a novel gene required for efficient homolog disjunction during meiosis I.Cell cycle (Georgetown, Tex.) · 2010Article
- Fused sister kinetochores initiate the reductional division in meiosis I.Nature cell biology · 2009Article
- The evolution of meiosis from mitosis.Genetics · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In meiosis I, two chromatids move to each spindle pole. Then, in meiosis II, the two are distributed, one to each future gamete. This requires that meiosis I chromosomes attach to the spindle differently than meiosis II chromosomes and that they regulate chromosome cohesion differently. We investigated whether the information that dictates the division type of the chromosome comes from the whole cell, the spindle, or the chromosome itself. Also, we determined when chromosomes can switch from meiosis I behavior to meiosis II behavior. We used a micromanipulation needle to fuse grasshopper spermatocytes in meiosis I to spermatocytes in meiosis II, and to move chromosomes from one spindle to the other. Chromosomes placed on spindles of a different meiotic division always behaved as they would have on their native spindle; e.g., a meiosis I chromosome attached to a meiosis II spindle in its normal fashion and sister chromatids moved together to the same spindle pole. We also showed that meiosis I chromosomes become competent meiosis II chromosomes in anaphase of meiosis I, but not before. The patterns for attachment to the spindle and regulation of cohesion are built into the chromosome itself. These results suggest that regulation of chromosome cohesion may be linked to differences in the arrangement of kinetochores in the two meiotic divisions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.