ArticleAntimicrobial agents and chemotherapy2000
In vitro antimicrobial properties of recombinant ASABF, an antimicrobial peptide isolated from the nematode Ascaris suum.
Article in Antimicrobial agents and chemotherapy, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Worms' Antimicrobial Peptides.Marine drugs · 2019Review
- Reciprocal Interactions between Nematodes and Their Microbial Environments.Frontiers in cellular and infection microbiology · 2017Review
- Overexpression of an antimicrobial peptide derived from C. elegans using an aggregation-prone protein coexpression system.AMB Express · 2013Article
- C. elegans: model host and tool for antimicrobial drug discovery.Disease models & mechanisms · 2011Review
- Generation of novel cationic antimicrobial peptides from natural non-antimicrobial sequences by acid-amide substitution.Annals of clinical microbiology and antimicrobials · 2011Article
- Inducible ASABF-type antimicrobial peptide from the sponge Suberites domuncula: microbicidal and hemolytic activity in vitro and toxic effect on molluscs in vivo.Marine drugs · 2011Article
- An enhancer peptide for membrane-disrupting antimicrobial peptides.BMC microbiology · 2010Article
- Cecropin P1 and novel nematode cecropins: a bacteria-inducible antimicrobial peptide family in the nematode Ascaris suum.The Biochemical journal · 2005Article
- Production of enterocin P, an antilisterial pediocin-like bacteriocin from Enterococcus faecium P13, in Pichia pastoris.Antimicrobial agents and chemotherapy · 2005Article
- Induction of ASABF (Ascaris suum antibacterial factor)-type antimicrobial peptides by bacterial injection: novel members of ASABF in the nematode Ascaris suum.The Biochemical journal · 2003Article
- abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis elegans.The Biochemical journal · 2002Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ASABF is a CSalphabeta-type antimicrobial peptide that contains four intramolecular disulfide bridges (Y. Kato and S. Komatsu, J. Biol. Chem. 271:30493-30498, 1996). In the present study, a recombinant ASABF was produced by using a yeast expression system, and its antimicrobial activity was characterized in detail. The recombinant ASABF was active against all gram-positive bacteria tested (7 of 7; minimum bactericidal concentration [MBC], 0.03 to 1 microg/ml) except Leuconostoc mesenteroides, some gram-negative bacteria (8 of 14; MBC, >0.5 microg/ml), and some yeasts (3 of 9; MBC >3 microg/ml). Slight hemolytic activity (4.2% at 100 microg/ml) against human erythrocytes was observed only under low-ionic-strength conditions. Less than 1 min of contact was enough to kill Staphylococcus aureus ATCC 6538P. The bactericidal activity against S. aureus was inhibited by salts.
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