ArticleJournal of bacteriology2000
Revised translation start site for secM defines an atypical signal peptide that regulates Escherichia coli secA expression.
Article in Journal of bacteriology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Patchy and widespread distribution of bacterial translation arrest peptides associated with the protein localization machinery.Nature communications · 2024Article
- Nascent SecM chain interacts with outer ribosomal surface to stabilize translation arrest.The Biochemical journal · 2020Article
- Increased freedom of movement in the nascent chain results in dynamic changes in the structure of the SecM arrest motif.Bioscience reports · 2019Article
- The Sec System: Protein Export inEcoSal Plus · 2017Review
- Exploration of the arrest peptide sequence space reveals arrest-enhanced variants.The Journal of biological chemistry · 2015Article
- A biphasic pulling force acts on transmembrane helices during translocon-mediated membrane integration.Nature structural & molecular biology · 2012Article
- Recruitment of a species-specific translational arrest module to monitor different cellular processes.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- SecM facilitates translocase function of SecA by localizing its biosynthesis.Genes & development · 2005Article
- Translocon "pulling" of nascent SecM controls the duration of its translational pause and secretion-responsive secA regulation.Journal of bacteriology · 2003Article
- Critical regions of secM that control its translation and secretion and promote secretion-specific secA regulation.Journal of bacteriology · 2002Article
- Genetic screen yields mutations in genes encoding all known components of the Escherichia coli signal recognition particle pathway.Journal of bacteriology · 2002Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The secretion-responsive regulation of Escherichia coli secA occurs by coupling its translation to the translation and secretion of an upstream regulator, secM (formerly geneX). We revise the translational start site for secM, defining a new signal peptide sequence with an extended amino-terminal region. Mutational studies indicate that certain atypical amino acyl residues within this extended region are critical for proper secA regulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.