ArticleGenome research2000
An annotated catalog of inverted repeats of Caenorhabditis elegans chromosomes III and X, with observations concerning odd/even biases and conserved motifs.
Article in Genome research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Regulation of gene expression by the action of a fungal lncRNA on a transactivator.RNA biology · 2020Article
- A new way to visualize DNA's base succession: the Caenorhabditis elegans chromosome landscapes.Medical & biological engineering & computing · 2015Article
- A MATLAB-based tool for accurate detection of perfect overlapping and nested inverted repeats in DNA sequences.Bioinformatics (Oxford, England) · 2014Article
- Compositional bias is a major determinant of the distribution pattern and abundance of palindromes in Drosophila melanogaster.Journal of molecular evolution · 2012Article
- The distribution of inverted repeat sequences in the Saccharomyces cerevisiae genome.Current genetics · 2010Article
- The most frequent short sequences in non-coding DNA.Nucleic acids research · 2010Article
- The human genome-wide distribution of DNA palindromes.Functional & integrative genomics · 2007Article
- Discovery and characterization of 91 novel transcripts expressed in cattle placenta.BMC genomics · 2007Article
- Evidence for active maintenance of inverted repeat structures identified by a comparative genomic approach.PloS one · 2007Article
- Public access for teaching genomics, proteomics, and bioinformatics.Cell biology education · 2003Article
- Meeting report: Incorporating genomics research into undergraduate curricula.Cell biology education · 2002Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have taken a computational approach to the problem of discovering and deciphering the grammar and syntax of gene regulation in eukaryotes. A logical first step is to produce an annotated catalog of all regulatory sites in a given genome. Likely candidates for such sites are direct and indirect repeats, including three subcategories of indirect repeats: inverted (palindromic), everted, and mirror-image repeats. To that end we have produced a searchable database of inverted repeats of chromosomes III and X of Caenorhabditis elegans, the first completely sequenced multicellular eukaryote. Initial results from the use of this catalog are observations concerning odd/even biases in perfect IRs. The potential usefulness of the catalog as a discovery tool for promoters was shown for some of the genes involved with G-protein functions and for heat shock protein 104 (hsp104).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.