Evidence map›Paper›PMID 10984454›Full record

ArticleGenome research2000

An ordered comparative map of the cattle and human genomes.

M R Band, J H Larson, M Rebeiz, C A Green, D W Heyen, J Donovan, R Windish, C Steining, P Mahyuddin, J E Womack and 1 more

Abstract readComparative Study
In one paragraph

Article in Genome research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed.

  1. Article
  2. Triamcinolone acetonide has minimal effect on short- and long-term metabolic activities of cartilage.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024
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  9. An Evaluation of theFrontiers in immunology · 2020
    Review
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  15. Article
  16. Profile of Harris A. Lewin.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  17. Article
  18. Article
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

M R BandDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
J H Larson
M Rebeiz
C A Green
D W Heyen
J Donovan
R Windish
C Steining
P Mahyuddin
J E Womack
H A Lewin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A cattle-human whole-genome comparative map was constructed using parallel radiation hybrid (RH) mapping in conjunction with EST sequencing, database mining for unmapped cattle genes, and a predictive bioinformatics approach (COMPASS) for targeting specific homologous regions. A total of 768 genes were placed on the RH map in addition to 319 microsatellites used as anchor markers. Of these, 638 had human orthologs with mapping data, thus permitting construction of an ordered comparative map. The large number of ordered loci revealed > or =105 conserved segments between the two genomes. The comparative map suggests that 41 translocation events, a minimum of 54 internal rearrangements, and repositioning of all but one centromere can account for the observed organizations of the cattle and human genomes. In addition, the COMPASS in silico mapping tool was shown to be 95% accurate in its ability to predict cattle chromosome location from random sequence data, demonstrating this tool to be valuable for efficient targeting of specific regions for detailed mapping. The comparative map generated will be a cornerstone for elucidating mammalian chromosome phylogeny and the identification of genes of agricultural importance."Ought we, for instance, to begin by discussing each separate species-in virtue of some common element of their nature, and proceed from this as a basis for the consideration of them separately?" from Aristotle, On the Parts of Animals, 350 B.C.E.

Indexed as

Genome, HumanAnimalsCattleChromosome MappingExpressed Sequence TagsFemaleGenesGenetic LinkageHumansMolecular Sequence DataReproducibility of Results

Identifiers

PMID10984454
PMCPMC310912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.