Evidence map›Paper›PMID 10981041›Full record

ReviewCurrent hypertension reports

Gene-environment interactions in hypertension.

Z Pausova, J Tremblay, P Hamet

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Association of connexin gene polymorphism with essential hypertension in Kazak and Han Chinese in Xinjiang, China.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2017
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Telomeres: the time factor in essential hypertension.Current hypertension reports · 2001
    Review
  13. Transitory and long-lasting effects of social stress and social isolation during the juvenile period on arterial pressure in rats.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Z PausovaLaboratory of Molecular Medicine and Cellular Biology of Hypertension, Centre hospitalier de l'Université de Montréal, 3850 St. Urbain Street, Montreal, Quebec H2W 1T8, Canada.
J Tremblay
P Hamet
Université de Montréal · CA

Funding

SCOR-MOLECULAR GENTICS OF HYPERTENSIONP50HL054998 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI JACOB, HOWARD J · 1996 to 2005
$8.1M
NHLBI NIH HHS 5 P50 HL 54998-02
6 · The paper itself

Abstract

Environmental factors such as stress, diet, and physical activity have long been recognized as playing an important role in the pathogenesis of essential hypertension. Individuals may vary in their response to these factors depending on differences in genes determining physiologic systems that mediate the response. In this article we discuss gene-environment interactions that contribute to the development of essential hypertension (environmental susceptibility to hypertension) and those that are involved in control of the disease (pharmacogenetics).

Indexed as

Life StyleSocial EnvironmentAnimalsGenetic Predisposition to DiseaseHumansHypertensionRatsRats, Inbred StrainsRisk Factors

Identifiers

PMID10981041
OpenAlexW2065430850

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.