ArticleThe Biochemical journal2000
A novel mechanism of xylan binding by a lectin-like module from Streptomyces lividans xylanase 10A.
Article in The Biochemical journal, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 62 citations in OpenAlex.
- Article
- Characterization of a GH Family 43 β-Xylosidase Having a Novel Carbohydrate-binding Module fromJournal of applied glycoscience · 2022Article
- Improving Hydrolysis Characteristics of Xylanases by Site-Directed Mutagenesis in Binding-Site Subsites from Streptomyces L10608.International journal of molecular sciences · 2018Article
- Extrinsic Functions of Lectin Domains in O-N-Acetylgalactosamine Glycan Biosynthesis.The Journal of biological chemistry · 2016Article
- Bioinformatic characterisation of genes encoding cell wall degrading enzymes in the Phytophthora parasitica genome.BMC genomics · 2014Article
- Inference of phenotype-defining functional modules of protein families for microbial plant biomass degraders.Biotechnology for biofuels · 2014Article
- Critical roles of Asp270 and Trp273 in the α-repeat of the carbohydrate-binding module of endo-1,3-β-glucanase for laminarin-binding avidity.Glycoconjugate journal · 2012Article
- CBM3d, a novel subfamily of family 3 carbohydrate-binding modules identified in Cel48A exoglucanase of Cellulosilyticum ruminicola.Journal of bacteriology · 2011Article
- Biochemical and domain analyses of FSUAxe6B, a modular acetyl xylan esterase, identify a unique carbohydrate binding module in Fibrobacter succinogenes S85.Journal of bacteriology · 2010Article
- A beta-l-Arabinopyranosidase from Streptomyces avermitilis is a novel member of glycoside hydrolase family 27.The Journal of biological chemistry · 2009Article
- Crystallization and preliminary crystallographic analysis of beta-L-arabinopyranosidase from Streptomyces avermitilis NBRC14893.Acta crystallographica. Section F, Structural biology and crystallization communications · 2009Article
- The catalytic and lectin domains of UDP-GalNAc:polypeptide alpha-N-Acetylgalactosaminyltransferase function in concert to direct glycosylation site selection.The Journal of biological chemistry · 2008Article
- Characterization of an exo-beta-1,3-galactanase from Clostridium thermocellum.Applied and environmental microbiology · 2006Article
- Carbohydrate-binding modules: fine-tuning polysaccharide recognition.The Biochemical journal · 2004Review
- Human glycolipid transfer protein: probing conformation using fluorescence spectroscopy.Biochemistry · 2004Article
- Structural basis for the unusual carbohydrate-binding specificity of jacalin towards galactose and mannose.The Biochemical journal · 2002Article
- Lipolytic activity of ricin from Ricinus sanguineus and Ricinus communis on neutral lipids.The Biochemical journal · 2001Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The C-terminal module of xylanase 10A from Streptomyces lividans is a family 13 carbohydrate-binding module (CBM13). CBM13 binds mono- and oligo-saccharides with association constants of approximately 1x10(2) M(-1)-1x10(3) M(-1). It appears to be specific only for pyranose sugars. CBM13 binds insoluble and soluble xylan, holocellulose, pachyman, lichenan, arabinogalactan and laminarin. The association constant for binding to soluble xylan is (6.2+/-0. 6)x10(3)/mol of xylan polymer. Site-directed mutation indicates the involvement of three functional sites on CBM13 in binding to soluble xylan. The sites are similar in sequence, and are predicted to have similar structures, to the alpha, beta and gamma sites of ricin toxin B-chain, which is also in family 13. The affinity of a single binding site on CBM13 for soluble xylan is only approximately (0. 5+/-0.1)x10(3)/mol of xylan. The binding of CBM13 to soluble xylan involves additive and co-operative interactions between the three binding sites. This mechanism of binding has not previously been reported for CBMs binding polysaccharides. CBM13 is the first bacterial module from family 13 to be described in detail.
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Identifiers
10970811PMC1221329W2170710018What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.