ArticleThe Journal of physiology2000
Tetanus relaxation of fast skeletal muscles of the mouse made parvalbumin deficient by gene inactivation.
Article in The Journal of physiology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 59 citations in OpenAlex.
- Comprehensive Sequence Analysis of Parvalbumins in Fish and Their Comparison with Parvalbumins in Tetrapod Species.Biology · 2022Article
- What Is Parvalbumin for?Biomolecules · 2022Review
- Role of parvalbumin in fatigue-induced changes in force and cytosolic calcium transients in intact single mouse myofibers.Journal of applied physiology (Bethesda, Md. : 1985) · 2022Article
- Parvalbumin affects skeletal muscle trophism through modulation of mitochondrial calcium uptake.Cell reports · 2021Article
- Detection of Ca2+ transients near ryanodine receptors by targeting fluorescent Ca2+ sensors to the triad.The Journal of general physiology · 2021Article
- Cytosolic CaCold Spring Harbor perspectives in biology · 2020Review
- Soluble calcium-binding proteins (SCBPs) of the earthworm Lumbricus terrestris: possible role as relaxation factors in muscle.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2018Article
- Doublet stimulation increases CaThe Journal of general physiology · 2017Article
- Length-dependent Ca2+ activation in skeletal muscle fibers from mammalians.American journal of physiology. Cell physiology · 2016Article
- Voltage clamp methods for the study of membrane currents and SR Ca(2+) release in adult skeletal muscle fibres.Progress in biophysics and molecular biology · 2012Review
- Cytosolic Ca2+ buffers.Cold Spring Harbor perspectives in biology · 2010Review
- Altered myoplasmic Ca(2+) handling in rat fast-twitch skeletal muscle fibres during disuse atrophy.Pflugers Archiv : European journal of physiology · 2010Article
- Role of TRPC1 channel in skeletal muscle function.American journal of physiology. Cell physiology · 2010Article
- Is high concentration of parvalbumin a requirement for superfast relaxation?Journal of muscle research and cell motility · 2009Article
- Renal expression of parvalbumin is critical for NaCl handling and response to diuretics.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- KATP channel deficiency in mouse flexor digitorum brevis causes fibre damage and impairs Ca2+ release and force development during fatigue in vitro.The Journal of physiology · 2007Article
- Tail muscles become slow but fatigable in chronic sacral spinal rats with spasticity.Journal of neurophysiology · 2006Article
- Propagation in the transverse tubular system and voltage dependence of calcium release in normal and mdx mouse muscle fibres.The Journal of physiology · 2005Article
- Skeletal muscle NAD(P)H two-photon fluorescence microscopy in vivo: topology and optical inner filters.Biophysical journal · 2005Article
- The action potential-evoked sarcoplasmic reticulum calcium release is impaired in mdx mouse muscle fibres.The Journal of physiology · 2004Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effects of tetanus duration on the relaxation rate of extensor digitorum longus (EDL) and flexor digitorum brevis (FDB) muscles were studied in normal (wild-type, WT) and parvalbumin-deficient (PVKO) mice, at 20 C. In EDL of PVKO, the relaxation rate was low and unaffected by tetanus duration (< 3.2 s). In contrast, the relaxation rate of WT muscles decreased when tetanus duration increased from 0.2 to 3.2 s. In WT muscles, fast relaxation recovered as the rest interval increased. Specific effect of parvalbumin was asserted by calculating the difference in relaxation rate between WT and PVKO muscles. For EDL, the rate constant of relaxation slowing was 1.10 s-1 of tetanization; the rate constant of relaxation recovery was 0.05 s-1 of rest. In FDB, the effects of tetanus duration on WT and PVKO muscles were qualitatively similar to those observed in EDL. Relaxation slowing as tetanus duration increases, reflects the progressive saturation of parvalbumin by Ca2+, while recovery as rest interval increases reflects the return to Ca2+-free parvalbumin. At all tetanus durations, relaxation rate still remained slightly faster in WT muscles. This suggested that parvalbumin facilitates calcium traffic from myofibrils to the SR. No difference was found between WT and PVKO muscles for: (i) the expression of the fast isoforms of myosin heavy chains, (ii) the force-velocity relationship and maximal shortening velocity and (iii) the Ca2+-activated ATPase activity from isolated preparations of the sarcoplasmic reticulum (SR).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.