ReviewJournal of muscle research and cell motility2000
Variable surface loops and myosin activity: accessories to a motor.
Review in Journal of muscle research and cell motility, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 48 citations in OpenAlex.
- Electrostatic interaction of loop 1 and backbone of human cardiac myosin regulates the rate of ATP induced actomyosin dissociation.Journal of muscle research and cell motility · 2022Article
- FRET and optical trapping reveal mechanisms of actin activation of the power stroke and phosphate release in myosin V.The Journal of biological chemistry · 2020Article
- Five Alternative Myosin Converter Domains Influence Muscle Power, Stretch Activation, and Kinetics.Biophysical journal · 2018Article
- Mutational Spectrum of MYO15A and the Molecular Mechanisms of DFNB3 Human Deafness.Human mutation · 2016Article
- Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis.Journal of molecular biology · 2016Article
- Loop 2 of myosin is a force-dependent inhibitor of the rigor bond.Journal of muscle research and cell motility · 2014Article
- The mechanical properties of Drosophila jump muscle expressing wild-type and embryonic Myosin isoforms.Biophysical journal · 2010Article
- Article
- Functional diversity among a family of human skeletal muscle myosin motors.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Alternative versions of the myosin relay domain differentially respond to load to influence Drosophila muscle kinetics.Biophysical journal · 2008Article
- Invertebrate muscles: thin and thick filament structure; molecular basis of contraction and its regulation, catch and asynchronous muscle.Progress in neurobiology · 2008Review
- The B2 alternatively spliced isoform of nonmuscle myosin II-B lacks actin-activated MgATPase activity and in vitro motility.Biochemical and biophysical research communications · 2008Article
- An alternative domain near the ATP binding pocket of Drosophila myosin affects muscle fiber kinetics.Biophysical journal · 2006Article
- Molecular engineering of myosin.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2004Review
- Alternative N-terminal regions of Drosophila myosin heavy chain tune muscle kinetics for optimal power output.Biophysical journal · 2004Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The catalytic head of myosin is a globular structure that has historically been divided into three segments of 25, 50, and 20 kDa. The solvent-exposed, proteolytically-sensitive surface loops of myosin that join these three segments are highly variable in their sequences. While surface loops have not traditionally been thought to affect enzymatic activities, these loops lie near the ATP and actin-binding sites and have been implicated in the modulation of myosin's kinetic activities. In this work we review the wealth of data regarding the loops that has accumulated over the years and discuss the roles of the loops in contributing to the different activities displayed by different myosin isoforms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.