ReviewJournal of clinical pathology2000
Lipoprotein (a) and stroke.
Review in Journal of clinical pathology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Lower lipoprotein(a) levels in patients with acute lacunar infarction.IBRO neuroscience reports · 2026Article
- Lipoprotein(a) levels in Down syndrome: A conundrum.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Lipoprotein(a) and panvascular disease.Lipids in health and disease · 2025Review
- Lipoprotein(a) and Cardiovascular Risk in Asian Populations: A Comprehensive Review.Journal of lipid and atherosclerosis · 2025Review
- Serum lipoprotein(a) and reclassification of coronary heart disease risk; application of prediction in a cross-sectional analysis of an ongoing Iranian cohort.BMC public health · 2023Article
- Significantly higher atherosclerosis risks in patients with obstructive sleep apnea and non-alcoholic fatty liver disease.PloS one · 2021Observational
- Recurrent stroke: the role of thrombophilia in a large international pediatric stroke population.Haematologica · 2019Article
- Lipoprotein(a) and Risk of Ischemic Stroke in the REGARDS Study.Arteriosclerosis, thrombosis, and vascular biology · 2019Article
- Associations of plasma LP(a), Hcy and D-D levels with the subtype of ischemic cerebrovascular disease.Medicine · 2019Observational
- Lipoprotein(a) and abdominal aortic aneurysm risk: The Atherosclerosis Risk in Communities study.Atherosclerosis · 2018Article
- The relationship between serum lipoprotein (a) levels and ischemic stroke risk: a cohort study in the Chinese population.Inflammation · 2014Article
- Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- Lipoprotein(a) in cardiovascular diseases.BioMed research international · 2013Review
- Correlative study between neuron-specific enolase and blood sugar level in ischemic stroke patients.Journal of neurosciences in rural practice · 2011Article
- Lipoprotein (a) and other Lipid Profile in Patients with Thrombotic Stroke: Is it a Reliable Marker?Journal of laboratory physicians · 2011Article
- Clinical and genetic features in a family with CADASIL and high lipoprotein (a) values.Journal of neurology · 2010Article
- Lipoprotein(a) predicts progression of carotid artery intima-media thickening in patients with type 2 diabetes: A four-year follow-up.Wiener klinische Wochenschrift · 2010Article
- Vascular risk factors, cognitive decline, and dementia.Vascular health and risk management · 2008Review
- Trombophilic screening for nonarteritic anterior ischemic optic neuropathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2006Article
- A prospective study of lipoprotein(a) and risk of coronary heart disease among women with type 2 diabetes.Diabetologia · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Strokes are one of the most common causes of mortality and long term severe disability. There is evidence that lipoprotein (a) (Lp(a)) is a predictor of many forms of vascular disease, including premature coronary artery disease. Several studies have also evaluated the association between Lp(a) and ischaemic (thrombotic) stroke. Several cross sectional (and a few prospective) studies provide contradictory findings regarding Lp(a) as a predictor of ischaemic stroke. Several factors might contribute to the existing confusion--for example, small sample sizes, different ethnic groups, the influence of oestrogens in women participating in the studies, plasma storage before Lp(a) determination, statistical errors, and selection bias. This review focuses on the Lp(a) related mechanisms that might contribute to the pathogenesis of ischaemic stroke. The association between Lp(a) and other cardiovascular risk factors is discussed. Therapeutic interventions that can lower the circulating concentrations of Lp(a) and thus possibly reduce the risk of stroke are also considered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.