ArticleJournal of bacteriology2000
The Escherichia coli O111 and Salmonella enterica O35 gene clusters: gene clusters encoding the same colitose-containing O antigen are highly conserved.
Article in Journal of bacteriology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 51 citations in OpenAlex.
- High diversity of Escherichia coli causing invasive disease in neonates in Malawi poses challenges for O-antigen based vaccine approach.Communications medicine · 2025Article
- Large-scale genomic survey with deep learning-based method reveals strain-level phage specificity determinants.GigaScience · 2024Article
- Deciphering Phage-Host Specificity Based on the Association of Phage Depolymerases and Bacterial Surface Glycan with Deep Learning.bioRxiv : the preprint server for biology · 2023Article
- Specific Bacterial Cell Wall Components Influence the Stability of Coxsackievirus B3.Journal of virology · 2021Article
- The complete genome and comparative analysis of the phage phiC120 infecting multidrug-resistant Escherichia coli and Salmonella strains.G3 (Bethesda, Md.) · 2021Article
- Systems Biology and Pangenome ofmBio · 2019Article
- Biochemical characterization of an α1,2-colitosyltransferase from Escherichia coli O55:H7.Glycobiology · 2016Article
- Article
- Development of a DNA microarray for molecular identification of all 46 Salmonella O serogroups.Applied and environmental microbiology · 2013Article
- Rapid genoserotyping tool for classification of Salmonella serovars.Journal of clinical microbiology · 2011Article
- Structural studies of the Nudix GDP-mannose hydrolase from E. coli reveals a new motif for mannose recognition.Proteins · 2011Article
- Multiplex, bead-based suspension array for molecular determination of common Salmonella serogroups.Journal of clinical microbiology · 2007Article
- Sequence analysis of the rfb loci, encoding proteins involved in the biosynthesis of the Salmonella enterica O17 and O18 antigens: serogroup-specific identification by PCR.Applied and environmental microbiology · 2006Article
- Relationships of the Escherichia coli O157, O111, and O55 O-antigen gene clusters with those of Salmonella enterica and Citrobacter freundii, which express identical O antigens.Journal of bacteriology · 2004Article
- Molecular serotyping of Klebsiella species isolates by restriction of the amplified capsular antigen gene cluster.Journal of clinical microbiology · 2004Article
- Molecular analysis of the rfb O antigen gene cluster of Salmonella enterica serogroup O:6,14 and development of a serogroup-specific PCR assay.Applied and environmental microbiology · 2003Article
- Phylogenetic analysis of Salmonella, Shigella, and Escherichia coli strains on the basis of the gyrB gene sequence.Journal of clinical microbiology · 2002Article
- The O-antigen gene cluster of Escherichia coli O55:H7 and identification of a new UDP-GlcNAc C4 epimerase gene.Journal of bacteriology · 2002Article
- Multilocus sequence typing for characterization of clinical and environmental salmonella strains.Journal of clinical microbiology · 2002Article
- Sequence analysis of four Shigella boydii O-antigen loci: implication for Escherichia coli and Shigella relationships.Infection and immunity · 2001Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
O antigen is part of the lipopolysaccharide present in the outer membrane of gram-negative bacteria. Escherichia coli and Salmonella enterica each have many forms of O antigen, but only three are common to the two species. It has been found that, in general, O-antigen genes are of low GC content. This deviation in GC content from that of typical S. enterica or E. coli genes (51%) is thought to indicate that the O-antigen DNA originated in species other than S. enterica or E. coli and was captured by lateral transfer. The O-antigen structure of Salmonella enterica O35 is identical to that of E. coli O111, commonly found in enteropathogenic E. coli strains. This O antigen, which has been shown to be a virulence factor in E. coli, contains colitose, a 3,6-dideoxyhexose found only rarely in the Enterobacteriaceae. Sequencing of the O35-antigen gene cluster of S. enterica serovar Adelaide revealed the same gene order and flanking genes as in E. coli O111. The divergence between corresponding genes of these two gene clusters at the nucleotide level ranges from 21.8 to 11.7%, within the normal range of divergence between S. enterica and E. coli. We conclude that the ancestor of E. coli and S. enterica had an O antigen identical to the O111 and O35 antigens, respectively, of these species and that the gene cluster encoding it has survived in both species.
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