ArticleGenome research2000
Ecologic genomics of DNA: upstream bending in prokaryotic promoters.
Article in Genome research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 41 citations in OpenAlex.
- Some novel features of strong promoters discovered in Cytophaga hutchinsonii.Applied microbiology and biotechnology · 2022Article
- The Potential Link between Thermal Resistance and Virulence inFrontiers in veterinary science · 2017Review
- Assessing diversity of DNA structure-related sequence features in prokaryotic genomes.DNA research : an international journal for rapid publication of reports on genes and genomes · 2014Article
- Investigating the interplay between nucleoid-associated proteins, DNA curvature, and CRISPR elements using comparative genomics.PloS one · 2014Article
- Genome-wide analysis of promoters: clustering by alignment and analysis of regular patterns.PloS one · 2014Article
- Promoters of Escherichia coli versus promoter islands: function and structure comparison.PloS one · 2013Article
- Differences in DNA curvature-related sequence periodicity between prokaryotic chromosomes and phages, and relationship to chromosomal prophage content.BMC genomics · 2012Article
- PerPlot & PerScan: tools for analysis of DNA curvature-related periodicity in genomic nucleotide sequences.Microbial informatics and experimentation · 2011Article
- E. coli DNA associated with isolated Hfq interacts with Hfq's distal surface and C-terminal domain.Biochimica et biophysica acta · 2010Article
- Comparative analysis of sequence periodicity among prokaryotic genomes points to differences in nucleoid structure and a relationship to gene expression.Journal of bacteriology · 2010Article
- Anatomy of Escherichia coli sigma70 promoters.Nucleic acids research · 2007Article
- The distinctive signatures of promoter regions and operon junctions across prokaryotes.Nucleic acids research · 2006Article
- Involvement of DNA curvature in intergenic regions of prokaryotes.Nucleic acids research · 2006Article
- A-tract clusters may facilitate DNA packaging in bacterial nucleoid.Nucleic acids research · 2005Article
- Sequence periodicity of Escherichia coli is concentrated in intergenic regions.BMC molecular biology · 2004Article
- Centromere parC of plasmid R1 is curved.Nucleic acids research · 2004Article
- Conservation of DNA curvature signals in regulatory regions of prokaryotic genes.Nucleic acids research · 2003Article
- Differential DNA binding of transcriptional regulator PcaU from Acinetobacter sp. strain ADP1.Journal of bacteriology · 2002Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
After our analysis of the distribution of predicted intrinsic curvature along all available complete prokaryotic genomes, the genomes were divided into two groups. Curvature distribution in all prokaryotes of the first group indicated a substantial fraction of promoters characterized by intrinsic DNA curvature located within or upstream of the promoter region. We did not find this peculiar DNA curvature distribution in prokaryotes in the second group. Remarkably, all bacteria of the first group were mesophilic, whereas many prokaryotes of the second group were hyperthermophilic. We hypothesize that DNA curvature plays a biologic role in gene regulation in mesophilic as opposed to hyperthermophilic prokaryotes, i.e., DNA curvature presumably has a functional adaptive significance determined by temperature selection.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.