ArticleGenome research2000
Alfresco--a workbench for comparative genomic sequence analysis.
Article in Genome research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 45 citations in OpenAlex.
- CGAS: comparative genomic analysis server.Bioinformatics (Oxford, England) · 2009Article
- CGAT: a comparative genome analysis tool for visualizing alignments in the analysis of complex evolutionary changes between closely related genomes.BMC bioinformatics · 2006Article
- Theatre: A software tool for detailed comparative analysis and visualization of genomic sequence.Nucleic acids research · 2003Article
- DNannotator: Annotation software tool kit for regional genomic sequences.Nucleic acids research · 2003Article
- Insights from human/mouse genome comparisons.Mammalian genome : official journal of the International Mammalian Genome Society · 2003Review
- Comparative genomic tools and databases: providing insights into the human genome.The Journal of clinical investigation · 2003Review
- Toucan: deciphering the cis-regulatory logic of coregulated genes.Nucleic acids research · 2003Article
- Identification of conserved regulatory elements by comparative genome analysis.Journal of biology · 2003Article
- CoreGenes: a computational tool for identifying and cataloging "core" genes in a set of small genomes.BMC bioinformatics · 2002Article
- Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome.Genome research · 2002Article
- Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5.Nucleic acids research · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
Comparative analysis of genomic sequences provides a powerful tool for identifying regions of potential biologic function; by comparing corresponding regions of genomes from suitable species, protein coding or regulatory regions can be identified by their homology. This requires the use of several specific types of computational analysis tools. Many programs exist for these types of analysis; not many exist for overall view/control of the results, which is necessary for large-scale genomic sequence analysis. Using Java, we have developed a new visualization tool that allows effective comparative genome sequence analysis. The program handles a pair of sequences from putatively homologous regions in different species. Results from various different existing external analysis programs, such as database searching, gene prediction, repeat masking, and alignment programs, are visualized and used to find corresponding functional sequence domains in the two sequences. The user interacts with the program through a graphic display of the genome regions, in which an independently scrollable and zoomable symbolic representation of the sequences is shown. As an example, the analysis of two unannotated orthologous genomic sequences from human and mouse containing parts of the UTY locus is presented.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.