ArticleArchives of disease in childhood2000
Prevalence of abnormal urinary albumin excretion in adolescents and children with insulin dependent diabetes: the MIDAC study. Microalbinuria in Diabetic Adolescents and Children (MIDAC) research group.
Article in Archives of disease in childhood, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 34 citations in OpenAlex.
- Usefulness of A Random Spot Urine Proteins-to-Creatinine Ratio to Screen for Increased Albuminuria in Patients with Type 1 Diabetes.Reports of biochemistry & molecular biology · 2025Article
- Article
- Prevalence and Factors Associated with Microalbuminuria in Pediatric Patients with Type 1 Diabetes Mellitus at a Large Tertiary-Level Hospital in Botswana.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- Long-term Outcomes in Youths with Diabetes Mellitus.Pediatric clinics of North America · 2015Review
- Factors associated with microalbuminuria in 7,549 children and adolescents with type 1 diabetes in the T1D Exchange clinic registry.Diabetes care · 2013Article
- Diabetic nephropathy in children and adolescents.Pediatric nephrology (Berlin, Germany) · 2008Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the prevalence of microalbuminuria, defined as an albumin to creatinine ratio (UAC) equal to or greater than 2 mg/mmol in at least two of three early morning urine samples, in adolescents and children with insulin dependent diabetes mellitus.
designCentrally coordinated, cross sectional, multicentre study in paediatric diabetes outpatient clinics in the United Kingdom and Republic of Ireland.
methodsBlood and urine samples collected between July 1997 and July 1998 were analysed at a central reference laboratory for HbA(1C) using high performance liquid chromatography, and for urinary albumin and creatinine concentrations from which the UAC was derived (mg/mmol). Clinical data were collected locally and coordinated centrally. SUBJECTS: Patients, aged between 10 and 20 years, with insulin dependent diabetes mellitus for more than a year, attending diabetes outpatient clinics.
resultsA total of 1007 patients, comprising 69% of the eligible population of 1451, provided three early morning urine samples. Ninety eight (9.7%) had microalbuminuria using the currently accepted screening cut off of UAC >/= 2 mg/mmol in at least two of three early morning urine samples. Significantly more girls than boys and significantly more pubertal and postpubertal patients had abnormal albumin excretion. Microalbuminuria was not associated with raised blood pressure.
conclusionsA prevalence of 9.7% for abnormal UAC was found in a cohort of 1007 children and adolescents aged 10-20 years. Thus a tenth of this national sample of young people were identified as being at particular risk of microvascular and later macrovascular disease.
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