ArticleGenetica1999
Genomes were forged by massive bombardments with retroelements and retrosequences.
Article in Genetica, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
67 citing papers in PubMed.
- Integrated Symbiotic Pleiotropy: Long Non-Coding RNAs and Disordered Proteins Interweaving the Functional Layers of the Eukaryotic Cell.International journal of molecular sciences · 2026Review
- Human endogenous retroviruses and the inflammatory response: A vicious circle associated with health and illness.Frontiers in immunology · 2022Review
- Comparative genome analysis of 52 fish species suggests differential associations of repetitive elements with their living aquatic environments.BMC genomics · 2018Article
- Article
- Deep landscape update of dispersed and tandem repeats in the genome model of the red jungle fowl, Gallus gallus, using a series of de novo investigating tools.BMC genomics · 2016Article
- Alternative Oxidase Gene Family in Hypericum perforatum L.: Characterization and Expression at the Post-germinative Phase.Frontiers in plant science · 2016Article
- Mammalian introns: when the junk generates molecular diversity.International journal of molecular sciences · 2015Review
- Transposable Element Insertions in Long Intergenic Non-Coding RNA Genes.Frontiers in bioengineering and biotechnology · 2015Article
- The persistent contributions of RNA to eukaryotic gen(om)e architecture and cellular function.Cold Spring Harbor perspectives in biology · 2014Review
- Interactions of noncanonical motifs with hnRNP A2 promote activity-dependent RNA transport in neurons.The Journal of cell biology · 2014Article
- Deep investigation of Arabidopsis thaliana junk DNA reveals a continuum between repetitive elements and genomic dark matter.PloS one · 2014Article
- Interaction-based evolution: how natural selection and nonrandom mutation work together.Biology direct · 2013Article
- Translational control at the synapse: role of RNA regulators.Trends in biochemical sciences · 2013Review
- Transposable elements and viruses as factors in adaptation and evolution: an expansion and strengthening of the TE-Thrust hypothesis.Ecology and evolution · 2012Article
- The endogenous retrovirus ENS-1 provides active binding sites for transcription factors in embryonic stem cells that specify extra embryonic tissue.Retrovirology · 2012Article
- Positive selection of co-opted mobile genetic elements in a mammalian gene: If you can't beat them, join them.Mobile genetic elements · 2012Article
- Article
- Article
- What Can Domesticated Genes Tell Us about the Intron Gain in Mammals?International journal of evolutionary biology · 2012Article
- Repetitive elements may comprise over two-thirds of the human genome.PLoS genetics · 2011Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Retroposition is an efficient route to move coding regions around the genome 'in search' of novel regulatory elements and to shotgun regulatory elements into the genome 'in search' of new target genes. The templates for such retrogenes are mRNAs, and for regulatory retronuons (nuon = any definable nucleic acid sequence) usually small non-mRNAs (snmRNAs). An example in support of the 'master gene' model for SINEs (short interspersed repetitive elements) is provided with neuronal BC1 RNA. Furthermore, an alternative explanation of LINE (long interspersed repetitive elements) involvement in the generation of SINEs is given. I will also argue that the status of transposable elements with respect to the host resembles more symbiosis than parasitiasis and that host defense is often lenient as if even to 'tolerate or support' retronuons. Finally the paradox of evolution's lack of foresight and the future exaptive use of retronuons is being dealt with by referring to W.F. Doolittle's 'Hierarchical Approaches to Genome Evolution'.
Indexed as
Identifiers
10952214What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.