ArticlePlant molecular biology2000
Electron transport controls transcription of the thioredoxin gene (trxA) in the cyanobacterium Synechocystis sp. PCC 6803.
Article in Plant molecular biology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 36 citations in OpenAlex.
- The sRNA NsiR4 fine-tunes arginine synthesis in the cyanobacteriumRNA biology · 2022Article
- The Novel PmBio · 2021Article
- Thioredoxin targets are regulated in heterocysts of cyanobacterium Anabaena sp. PCC 7120 in a light-independent manner.Journal of experimental botany · 2020Article
- Lethality caused by ADP-glucose accumulation is suppressed by salt-induced carbon flux redirection in cyanobacteria.Journal of experimental botany · 2020Article
- Identification of the direct regulon of NtcA during early acclimation to nitrogen starvation in the cyanobacterium Synechocystis sp. PCC 6803.Nucleic acids research · 2017Article
- The sRNA NsiR4 is involved in nitrogen assimilation control in cyanobacteria by targeting glutamine synthetase inactivating factor IF7.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- CopM is a novel copper-binding protein involved in copper resistance in Synechocystis sp. PCC 6803.MicrobiologyOpen · 2015Article
- Comparative protein expression in different strains of the bloom-forming cyanobacterium Microcystis aeruginosa.Molecular & cellular proteomics : MCP · 2011Article
- An experimentally anchored map of transcriptional start sites in the model cyanobacterium Synechocystis sp. PCC6803.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- A comprehensive analysis of the peroxiredoxin reduction system in the Cyanobacterium Synechocystis sp. strain PCC 6803 reveals that all five peroxiredoxins are thioredoxin dependent.Journal of bacteriology · 2009Article
- The glutathione/glutaredoxin system is essential for arsenate reduction in Synechocystis sp. strain PCC 6803.Journal of bacteriology · 2009Article
- The diversity and complexity of the cyanobacterial thioredoxin systems.Photosynthesis research · 2006Article
- Thioredoxin-linked processes in cyanobacteria are as numerous as in chloroplasts, but targets are different.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- DNA microarray analysis of redox-responsive genes in the genome of the cyanobacterium Synechocystis sp. strain PCC 6803.Journal of bacteriology · 2003Article
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3 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The trxA gene encoding one of the different thioredoxins of the facultative heterotrophic cyanobacterium Synechocystis sp. PCC 6803 is transcribed as a single mRNA of 450 nucleotides. Transcript accumulation is similar in all standard growth conditions but strongly decreases after transferring cell cultures from light to darkness. In steady-state conditions, trxA transcription is reduced at high (150-500 microE m(-2) s(-1)) compared with moderate (10-50 microE m(-2) s(-1)) light intensities. The stability of the trxA transcript was similar at different light intensities, and also in darkness. Photosynthetic electron transport inhibitors, as well as glucose starvation in a mutant strain lacking photosystem II, promote a strong decline in the level of trxA transcript. Primer extension analysis suggests that trxA is transcribed from two proximal promoters containing a -10 TATA box similar to the Escherichia coli consensus promoters. Unlike the trxA mRNA, the amount of thioredoxin protein was not reduced in the dark, neither at high light intensities, indicating that thioredoxin protein is very stable. Our results indicate that the thioredoxin encoded by the trxA gene is likely to be primarily regulated at the transcriptional level, rather than at the protein level, by the electron transport generated photosynthetically or from glucose metabolism.
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