ArticleThe Plant cell2000
A mitogen-activated protein kinase kinase required for induction of cytokinesis and appressorium formation by host signals in the conidia of Colletotrichum gloeosporioides.
Article in The Plant cell, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 70 citations in OpenAlex.
- Effects of Insect Cuticular Compounds on Appressorium Formation and Metabolic Activity inJournal of fungi (Basel, Switzerland) · 2025Article
- Analysis of the Effects ofJournal of fungi (Basel, Switzerland) · 2025Article
- Advances in understanding the mechanism of resistance to anthracnose and induced defence response in tea plants.Molecular plant pathology · 2023Review
- Ethylene Promotes Expression of the Appressorium- and Pathogenicity-Related Genes via GPCR- and MAPK-Dependent Manners inJournal of fungi (Basel, Switzerland) · 2022Article
- Involvement of Protein Kinase CgSat4 in Potassium Uptake, Cation Tolerance, and Full Virulence inFrontiers in plant science · 2022Article
- Recent progress on harm, pathogen classification, control and pathogenic molecular mechanism of anthracnose of oil-tea.Frontiers in microbiology · 2022Review
- Regulation of biotic interactions and responses to abiotic stresses by MAP kinase pathways in plant pathogenic fungi.Stress biology · 2021Review
- Quorum sensing-mediated inter-specific conidial anastomosis tube fusion between Colletotrichum gloeosporioides and C. siamense.IMA fungus · 2021Article
- Protein Kinase Signaling Pathways in Plant-Frontiers in plant science · 2021Review
- Hidden Allee effect in photosynthetic organisms.Communicative & integrative biology · 2020Article
- Lifestyle Characteristics and Gene Expression Analysis ofBiomolecules · 2020Article
- Acetyl-coenzyme A synthetase gene ChAcs1 is essential for lipid metabolism, carbon utilization and virulence of the hemibiotrophic fungus Colletotrichum higginsianum.Molecular plant pathology · 2019Article
- The MAPKKK CgMck1 Is Required for Cell Wall Integrity, Appressorium Development, and Pathogenicity inGenes · 2018Article
- Functional analysis of a regulator of G-protein signaling CgRGS1 in the rubber tree anthracnose fungus Colletotrichum gloeosporioides.Archives of microbiology · 2018Article
- The Mitogen-Activated Protein KinaseFrontiers in microbiology · 2017Article
- ChSte7 Is Required for Vegetative Growth and Various Plant Infection Processes in Colletotrichum higginsianum.BioMed research international · 2016Article
- Molecular Diagnosis of Pathogenic Sporothrix Species.PLoS neglected tropical diseases · 2015Article
- Physcomitrella patens Activates Defense Responses against the Pathogen Colletotrichum gloeosporioides.International journal of molecular sciences · 2015Article
- The evolution of ethylene signaling in plant chemical ecology.Journal of chemical ecology · 2014Review
- Inactivation of the catalytic subunit of cAMP-dependent protein kinase A causes delayed appressorium formation and reduced pathogenicity of Colletotrichum gloeosporioides.TheScientificWorldJournal · 2012Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Differentiation of fungal conidia of phytopathogens into the infection structure, appressorium, requires contact with a hard surface and host signals. The molecular signaling involved in the induction of this differentiation is poorly understood. We report the cloning of a mitogen-activated protein kinase kinase (MEK), CgMEK, from Colletotrichum gloeosporioides and its role in the induction of these developmental processes involved in pathogenesis. Disruption of CgMEK1 resulted in the loss of its ability to form appressoria in response to the host's signals and a loss of virulence. Results of confocal microscopic examination of germinating conidia of the gene-disrupted mutants were similar to those for wild-type conidia treated with an MEK inhibitor, suggesting that CgMEK1 is involved in two developmental processes in the differentiation into appressorium: (1) polarized cell division, with the preferential increase in F-actin in one of the daughter nuclei after nuclear division and the formation of septum; and (2) differentiation of the germ tube into an appressorium. CgMEK1 is required for the differentiation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.