ArticleThe Plant cell2000
Prenylation of the floral transcription factor APETALA1 modulates its function.
Article in The Plant cell, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
43 citing papers in PubMed, 107 citations in OpenAlex.
- Farnesol and geranylgeraniol in plant reproduction: insights from Arabidopsis and beyond.Journal of experimental botany · 2026Review
- Protein farnesylation: from molecular mechanisms to therapeutic targeting in cancer, aging, and beyond.Frontiers in pharmacology · 2026Review
- Protein Prenylation Makeovers in Plants: Insights into Substrate Diversification.International journal of molecular sciences · 2025Review
- Protein Prenylation in Plants: Mechanisms and Functional Implications.Plants (Basel, Switzerland) · 2025Review
- Methyl-Jasmonate Functions as a Molecular Switch Promoting Cross-Talk between Pathways for the Biosynthesis of Isoprenoid Backbones Used to Modify Proteins in Plants.Plants (Basel, Switzerland) · 2024Article
- Functional Conservation and Divergence of FiveGenes · 2021Article
- PARIS farnesylation prevents neurodegeneration in models of Parkinson's disease.Science translational medicine · 2021Article
- Protein Farnesylation Takes Part in Arabidopsis Seed Development.Frontiers in plant science · 2021Article
- Protein Prenylation in Plant Stress Responses.Molecules (Basel, Switzerland) · 2019Review
- Homeotic MADS-box genes encoding LeMADS-MC orthologues in wild tomato species (genus Solanum).Doklady. Biochemistry and biophysics · 2017Article
- Functional Divergence of APETALA1 and FRUITFULL is due to Changes in both Regulation and Coding Sequence.Frontiers in plant science · 2015Article
- Overexpression of two PsnAP1 genes from Populus simonii × P. nigra causes early flowering in transgenic tobacco and Arabidopsis.PloS one · 2014Article
- The role of lipid post-translational modification in plant developmental processes.Frontiers in plant science · 2014Review
- Turning moss into algae: prenylation targets in Physcomitrella patens.Plant signaling & behavior · 2014Article
- Evolution of fruit development genes in flowering plants.Frontiers in plant science · 2014Article
- Assessing duplication and loss of APETALA1/FRUITFULL homologs in Ranunculales.Frontiers in plant science · 2013Article
- Poppy APETALA1/FRUITFULL orthologs control flowering time, branching, perianth identity, and fruit development.Plant physiology · 2012Article
- De novo genome sequencing and comparative genomics of date palm (Phoenix dactylifera).Nature biotechnology · 2011Article
- Identification and characterization of flowering genes in kiwifruit: sequence conservation and role in kiwifruit flower development.BMC plant biology · 2011Article
- Molecular, genetic and transcriptional evidence for a role of VvAGL11 in stenospermocarpic seedlessness in grapevine.BMC plant biology · 2011Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Arabidopsis MADS box transcription factor APETALA1 (AP1) was identified as a substrate for farnesyltransferase and shown to be farnesylated efficiently both in vitro and in vivo. AP1 regulates the transition from inflorescence shoot to floral meristems and the development of sepals and petals. AP1 fused to green fluorescent protein (GFP) retained transcription factor activity and directed the expected terminal flower phenotype when ectopically expressed in transgenic Arabidopsis. However, ap1mS, a farnesyl cysteine-acceptor mutant of AP1, as well as the GFP-ap1mS fusion protein failed to direct the development of compound terminal flowers but instead induced novel phenotypes when ectopically expressed in Arabidopsis. Similarly, compound terminal flowers did not develop in era1-2 transformants that ectopically expressed AP1. Together, the results demonstrate that AP1 is a target of farnesyltransferase and suggest that farnesylation alters the function and perhaps specificity of the transcription factor.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.