ArticleInfection and immunity2000
Cl(-) secretion in colonic epithelial cells induced by the vibrio parahaemolyticus hemolytic toxin related to thermostable direct hemolysin.
Article in Infection and immunity, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 49 citations in OpenAlex.
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- Microbiological safety and hygiene monitoring of coastal seawater at Northern public beaches of Mauritius and genetic characterization of human pathogenic Vibrio species.PLOS global public health · 2026Article
- Unveiling potential virulence determinants inMicrobiology spectrum · 2024Article
- Comparison on the Growth Variability ofFrontiers in microbiology · 2020Article
- Bile Sensing: The Activation ofFrontiers in microbiology · 2017Article
- Prevalence, Antibiotic Susceptibility and Diversity ofFrontiers in microbiology · 2017Article
- Prevalence and Antimicrobial Susceptibility ofFrontiers in microbiology · 2017Article
- The pathogenesis, detection, and prevention of Vibrio parahaemolyticus.Frontiers in microbiology · 2015Article
- Roles of thermostable direct hemolysin (TDH) and TDH-related hemolysin (TRH) in Vibrio parahaemolyticus.Frontiers in microbiology · 2014Review
- Fitness factors in vibrios: a mini-review.Microbial ecology · 2013Review
- Distribution and dynamics of epidemic and pandemic Vibrio parahaemolyticus virulence factors.Frontiers in cellular and infection microbiology · 2013Review
- The Vibrio parahaemolyticus ToxRS regulator is required for stress tolerance and colonization in a novel orogastric streptomycin-induced adult murine model.Infection and immunity · 2012Article
- The Vibrio parahaemolyticus Type III Secretion Systems manipulate host cell MAPK for critical steps in pathogenesis.BMC microbiology · 2010Article
- Development of two animal models to study the function of Vibrio parahaemolyticus type III secretion systems.Infection and immunity · 2010Article
- Effect on human cells of environmental Vibrio parahaemolyticus strains carrying type III secretion system 2.Infection and immunity · 2010Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A hemolytic toxin related to thermostable direct hemolysin (TDH), TDH-related hemolysin (TRH), produced by Kanagawa-phenomenon-negative Vibrio parahaemolyticus is suspected of playing an important, but yet-to-be-elucidated role in diarrhea caused by this organism. In cultured human colonic epithelial cells, TRH increases Cl(-) secretion, followed by elevation of intracellular calcium.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.