ReviewDrug safety2000
The value of reporting therapeutic ineffectiveness as an adverse drug reaction.
Review in Drug safety, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Detection of adverse drug events in e-prescribing and administrative health data: a validation study.BMC health services research · 2021Article
- Pharmacovigilance of suspected or confirmed therapeutic ineffectiveness of artemisinin-based combination therapy: extent, associated factors, challenges and solutions to reporting.Malaria journal · 2020Article
- Article
- The development and evaluation of triage algorithms for early discovery of adverse drug interactions.Drug safety · 2013Article
- Suspected adverse drug reactions reported for children worldwide: an exploratory study using VigiBase.Drug safety · 2011Article
- Reporting patterns indicative of adverse drug interactions: a systematic evaluation in VigiBase.Drug safety · 2011Article
- Evaluation of patients' experiences with antidepressants reported by means of a medicine reporting system.European journal of clinical pharmacology · 2007Article
- Therapeutic ineffectiveness: heads or tails?Drug safety · 2002Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Therapeutic ineffectiveness is a frequent drug-related problem that can occur in a variety of different situations and be caused by different mechanisms. Examples are inappropriate use, interactions or metabolic abnormalities. Observations in patients of unexpected ineffectiveness can provide important information with regard to such situations. Therefore, ineffectiveness--especially when unexpected or unexplained--is a potentially important reportable event in pharmacovigilance. The terms regarding ineffectiveness in the WHO Adverse Reaction Terminology (WHOART) have been recently revised in order to enable optimal coding of such case reports.
Indexed as
Identifiers
10945372What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.