ReviewImmunologic research2000
Modulation of autoimmune diseases by nitric oxide.
Review in Immunologic research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 100 citations in OpenAlex.
- Nitric oxide modulates UDP-evoked cytosolic transients via P2YScientific reports · 2025Article
- Towards a map of the immune system manipulation network byFrontiers in cellular and infection microbiology · 2025Review
- Bioactive Diterpenes, Norditerpenes, and Sesquiterpenes from a Formosan Soft CoralPharmaceuticals (Basel, Switzerland) · 2021Article
- Brazilian medicinal plants with corroborated anti-inflammatory activities: a review.Pharmaceutical biology · 2018Review
- A Novel HPLC Method for Direct Detection of Nitric Oxide Scavengers from Complex Plant Matrices and Its Application toMolecules (Basel, Switzerland) · 2018Article
- Evaluation of the Potential Association between NOS Gene Polymorphisms (iNOS G-954C and eNOS G894T) and Psoriasis.Annals of dermatology · 2016Article
- Inducible nitric oxide synthase response and associated cytokine gene expression in the spleen of mice infected with Clonorchis sinensis.Parasitology research · 2015Article
- Antioxidative, anti-inflammatory, and matrix metalloproteinase inhibitory activities of 20(S)-ginsenoside Rg3 in cultured mammalian cell lines.Molecular biology reports · 2013Article
- Anti-Inflammatory, Antioxidant, Anti-Angiogenic and Skin Whitening Activities of Phryma leptostachya var. asiatica Hara Extract.Biomolecules & therapeutics · 2013Article
- Endothelial nitric oxide synthase inhibits the development of autoimmune-mediated vasculitis in mice.Arthritis and rheumatism · 2012Article
- Biological Activities of Libidibia (Caesalpinia) ferrea var. parvifolia (Mart. ex Tul.) L. P. Queiroz Pod Preparations.Evidence-based complementary and alternative medicine : eCAM · 2012Article
- Anti-inflammatory activity of n-propyl gallate through down-regulation of NF-κB and JNK pathways.Inflammation · 2011Article
- Analysis of inducible nitric oxide synthase gene polymorphisms in vitiligo in Han Chinese people.PloS one · 2011Article
- IL-2 and IFN-gamma in the retina of diabetic rats.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2010Article
- Estrogen regulates transcription factors STAT-1 and NF-kappaB to promote inducible nitric oxide synthase and inflammatory responses.Journal of immunology (Baltimore, Md. : 1950) · 2009Article
- Inhibition of nitric oxide synthase exacerbates group B streptococcus sepsis and arthritis in mice.Infection and immunity · 2004Article
- Serum nitric oxide (NO) levels in systemic sclerosis patients: correlation between NO levels and clinical features.Clinical and experimental immunology · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitric oxide (NO) is an intercellular messenger that performs a number of functions, including neurotransmission, vasodilatation, inhibition of platelet aggregation, and modulation of leukocyte adhesion. NO has recently been shown to act as a potent cytotoxic effector molecule as well as to play an important role in the pathogenesis of organ-specific autoimmunity. NO may also modulate the immune response by interfering with Th1/Th2 balance in autoimmune diseases. This review will discuss the role of NO and nitric oxide synthase (NOS) in pathophysiologic and therapeutic implications in various autoimmune diseases with particular reference to T helper-1 (Th1) and T helper-2 (Th2) cytokines.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.