ReviewRNA (New York, N.Y.)2000
Emerging features of mRNA decay in bacteria.
Review in RNA (New York, N.Y.), 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 144 citations in OpenAlex.
- Bacterial single-cell transcriptomics: Recent technical advances and future applications in dentistry.The Japanese dental science review · 2023Review
- Tyrosine phosphorylation controlled poly(A) polymerase I activity regulates general stress response in bacteria.Life science alliance · 2023Article
- Accessibility of the Shine-Dalgarno Sequence Dictates N-Terminal Codon Bias in E. coli.Molecular cell · 2018Article
- Global survey of mRNA levels and decay rates ofHeliyon · 2017Article
- Scaling by shrinking: empowering single-cell 'omics' with microfluidic devices.Nature reviews. Genetics · 2017Review
- Acclimation of Antarctic Chlamydomonas to the sea-ice environment: a transcriptomic analysis.Extremophiles : life under extreme conditions · 2016Article
- Enhanced production of L-sorbose from D-sorbitol by improving the mRNA abundance of sorbitol dehydrogenase in Gluconobacter oxydans WSH-003.Microbial cell factories · 2014Article
- Antibiotic stress-induced modulation of the endoribonucleolytic activity of RNase III and RNase G confers resistance to aminoglycoside antibiotics in Escherichia coli.Nucleic acids research · 2014Article
- Genome-wide analysis of poly(A) site selection in Schizosaccharomyces pombe.RNA (New York, N.Y.) · 2013Article
- A VapBC toxin-antitoxin module is a posttranscriptional regulator of metabolic flux in mycobacteria.Journal of bacteriology · 2012Article
- Bacterial transcriptomics: what is beyond the RNA horiz-ome?Nature reviews. Microbiology · 2011Review
- The stoichiometry of the Escherichia coli Hfq protein bound to RNA.RNA (New York, N.Y.) · 2011Article
- Article
- Messenger RNA processing in Methanocaldococcus (Methanococcus) jannaschii.RNA (New York, N.Y.) · 2009Article
- Messenger RNA Turnover Processes in Escherichia coli, Bacillus subtilis, and Emerging Studies in Staphylococcus aureus.International journal of microbiology · 2009Article
- Genomic analysis of the role of RNase R in the turnover of Pseudomonas putida mRNAs.Journal of bacteriology · 2008Article
- Article
- The deleterious effect of an insertion sequence removing the last twenty percent of the essential Escherichia coli rpsA gene is due to mRNA destabilization, not protein truncation.Journal of bacteriology · 2007Article
- Mechanisms of physiological regulation of RNA synthesis in bacteria: new discoveries breaking old schemes.Journal of applied genetics · 2007Review
- Antisense RNA based down-regulation of RNaseE in E. coli.Microbial cell factories · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The problem of mRNA decay in E. coli has recently seen exciting progress, with the discoveries that key degradation enzymes are associated together in a high molecular weight degradosome and that polyadenylation promotes decay. Recent advances make it clear that mRNA decay in bacteria is far more interesting enzymatically than might have been predicted. In-depth study of specific mRNAs has revealed multiple pathways for degradation. Which pathway a given mRNA follows appears to depend in large part on the location of the initiating endonucleolytic cleavage within the mRNA. During the steps of mRNA decay, stable RNA structures pose formidable barriers to the 3' --> 5' exonucleases. However, polyadenylation is now emerging as a process that plays an important role in maintaining the momentum of exonucleolytic degradation by adding single-stranded extensions to the 3' ends of mRNAs and their decay intermediates, thereby facilitating further exonuclease digestion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.