ArticleThe Journal of infection2000
Persistence of viruses in upper respiratory tract of children with asthma.
Article in The Journal of infection, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Prevalence of respiratory viruses in stable and acute asthma: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- Viruses in chronic rhinosinusitis: a systematic review.Frontiers in allergy · 2023Review
- Article
- Adenoviruses in medicine: innocuous pathogen, predator, or partner.Trends in molecular medicine · 2023Review
- Mouse Adenovirus Type 1 Persistence Exacerbates Inflammation Induced by Allogeneic Bone Marrow Transplantation.Journal of virology · 2022Article
- Pediatric asthma and COVID-19: The known, the unknown, and the controversial.Pediatric pulmonology · 2020Review
- Managing Asthma during Coronavirus Disease-2019: An Example for Other Chronic Conditions in Children and Adolescents.The Journal of pediatrics · 2020Review
- Host Antiviral Response Suppresses Ciliogenesis and Motile Ciliary Functions in the Nasal Epithelium.Frontiers in cell and developmental biology · 2020Article
- Human adenovirus replication and persistence in hypertrophic adenoids and palatine tonsils in children.Journal of medical virology · 2019Article
- Modulation of airway hyperresponsiveness by rhinovirus exposure.Respiratory research · 2018Review
- Diagnosis of Pediatric Acute Adenovirus Infections: Is a Positive PCR Sufficient?The Pediatric infectious disease journal · 2016Article
- Presence of rhinovirus in the respiratory tract of adolescents and young adults with asthma without symptoms of infection.Respiratory medicine · 2016Article
- Viral coinfection in acute respiratory infection in Mexican children treated by the emergency service: A cross-sectional study.Italian journal of pediatrics · 2015Article
- Infection in severe asthma exacerbations and critical asthma syndrome.Clinical reviews in allergy & immunology · 2015Review
- Adenovirus species C is associated with chronic suppurative lung diseases in children.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2014Article
- High rates of detection of respiratory viruses in the nasal washes and mucosae of patients with chronic rhinosinusitis.Journal of clinical microbiology · 2013Article
- Response to infections in patients with asthma and atopic disease: an epiphenomenon or reflection of host susceptibility?The Journal of allergy and clinical immunology · 2012Review
- Molecular evolution of human species D adenoviruses.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2011Article
- Persistence of rhinovirus RNA and IP-10 gene expression after acute asthma.Respirology (Carlton, Vic.) · 2011Article
- Viral diversity in asthma.Immunology and allergy clinics of North America · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesNasopharyngeal swabs of 50 asthmatic children in the symptom-free period were examined for the presence of adenoviruses, rhinoviruses and coronaviruses. A control group of 20 healthy individuals was included in this study.
methodsA polymerase chain reaction was used to detect adenovirus DNA and rhinovirus and coronavirus complementary DNA. The fragments of amplified genetic material were visualized with the use of agarose gel electrophoresis.
resultsAdenovirus DNA was found in 78.4% of asthmatic children, rhinovirus RNA in 32.4% and coronavirus RNA in 2.7%. Adenovirus DNA was detected in one of the 20 nasopharyngeal swabs of healthy controls; the rest of the control samples were negative.
conclusionsThe persistent presence of viruses in the upper respiratory tract of asthmatic children shows a possible connection between viral infections and asthma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.