Evidence map›Paper›PMID 10940047›Full record

ArticleJournal of bacteriology2000

Plasmid pGS5 from the hyperthermophilic archaeon Archaeoglobus profundus is negatively supercoiled.

P López-García, P Forterre, J van der Oost, G Erauso

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. How Do Thermophiles Organize Their Genomes?Microbes and environments · 2024
    Review
  4. Article
  5. The regulation of DNA supercoiling across evolution.Protein science : a publication of the Protein Society · 2021
    Review
  6. Archaea: A Gold Mine for Topoisomerase Diversity.Frontiers in microbiology · 2021
    Review
  7. Article
  8. The enigmatic archaeal virosphere.Nature reviews. Microbiology · 2017
    Review
  9. Article
  10. Review
  11. Article
  12. DNA self-assembly: from chirality to evolution.International journal of molecular sciences · 2013
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

P López-GarcíaInstitut de Génétique et Microbiologie, Université Paris-Sud, 91405 Orsay Cedex, France. puri@umh.es
P Forterre
J van der Oost
G Erauso
Wageningen University & Research · NLUniversitat de Miguel Hernández d'Elx · ESUniversité Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present evidence that, in contrast to plasmids from other hyperthermophilic archaea, which are in the relaxed to positively supercoiled state, plasmid pGS5 (2.8 kb) from Archaeoglobus profundus is negatively supercoiled. This might be due to the presence of a gyrase introducing negative supercoils, since gyrase genes are present in the genome of its close relative A. fulgidus, and suggests that gyrase activity predominates over reverse gyrase whenever the two topoisomerases coexist in cells.

Indexed as

DNA, ArchaealDNA, SuperhelicalPlasmidsArchaeoglobusDNA, ArchaealDNA, Superhelical

Identifiers

PMID10940047
PMCPMC111383
OpenAlexW2148125475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.