Evidence map›Paper›PMID 10939710›Full record

ReviewJournal of clinical immunology2000

Molecular steps of cell suicide: an insight into immune senescence.

S Gupta

Abstract readComparative StudyReview
PubMed Publisher
In one paragraph

Review in Journal of clinical immunology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Antiapoptotic Effects of EGb 761.Evidence-based complementary and alternative medicine : eCAM · 2013
    Article
  8. Immunological outcomes of exercise in older adults.Clinical interventions in aging · 2007
    Review
  9. Article
  10. Review
  11. Article
  12. Ian4 is required for mitochondrial integrity and T cell survival.Proceedings of the National Academy of Sciences of the United States of America · 2003
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

S GuptaDepartment of Medicine, University of California, Irvine 92697, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cellular and molecular basis of immune senescence is unclear. A number of mechanisms have been proposed. In this issue of the Journal of Clinical Immunology, some of the mechanisms for various immunologic abnormalities in aging are presented. In this article, various molecular steps of both death receptor and mitochondrial pathways of apoptosis in general are reviewed. In particular, the role of apoptosis in T-cell immune senescence is discussed.

Indexed as

Arabidopsis ProteinsInsect ProteinsProteinsAdultAgedAged, 80 and overAgingAnimalsApoptosisBacterial ProteinsCaspase InhibitorsCaspasesCellular SenescenceCysteine Proteinase InhibitorsCytochrome c GroupElectron TransportArabidopsis ProteinsBacterial ProteinsCaspase InhibitorsCaspasesCysteine Proteinase InhibitorsCytochrome c GroupFad7 protein, ArabidopsisFASLG protein, humanFas Ligand ProteinFasl protein, mousefas ReceptorFatty Acid DesaturasesInhibitor of Apoptosis ProteinsInsect ProteinsMembrane GlycoproteinsProteinsProto-Oncogene Proteins c-bcl-2Receptors, Tumor Necrosis FactorTumor Necrosis Factor-alpha

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.