Evidence map›Paper›PMID 10939517›Full record

ArticleThe Histochemical journal2000

Colocalization of numerous immunoreactivities in endocrine cells of the chicken proventriculus at hatching.

A Martínez, A M Buchan, J López, P Sesma

Abstract read
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In one paragraph

Article in The Histochemical journal, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 67% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

A MartínezDepartment of Cytology and Histology, Universidad de Navarra, Pamplona, Spain.
A M Buchan
J López
P Sesma
Universidad de Navarra · ESUniversidad Autónoma de Madrid · ESUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The colocalization of regulatory peptide immunoreactivities in endocrine cells of the chicken proventriculus at hatching has been investigated using the avidin-biotin technique in serial sections and double immunofluorescence in the same section for light microscopy, and double immunogold staining for electron microscopy. In addition to the eight immunoreactivities previously described in this organ, cells immunoreactive for peptide histidine isoleucine (PHI), peptide gene product 9.5 (PGP), and the amidating enzyme, peptidylglycine alpha-amidating monooxygenase (PAM) were observed. All the cells immunoreactive to glucagon were also immunostained by the PHI antiserum. In addition, all the glucagon-like peptide 1, avian pancreatic polypeptide, and some of the neurotensin-like cells costored also glucagon- and PHI-immunoreactive substances. PGP- and PAM-immunoreactivities were also found in the glucagon-positive cells. A small proportion of the somatostatin-containing cells were positive for PHI but not for other regulatory peptides. These results could suggest either the existence of a very complex regulatory system or that the endocrine system of the newborn chickens is not yet fully developed.

Indexed as

Multienzyme ComplexesAnimalsBombesinChickensGlucagonGlucagon-Like Peptide 1Mixed Function OxygenasesPancreatic PolypeptidePeptide FragmentsPeptide PHIProtein PrecursorsProventriculusSerotoninThiolester HydrolasesUbiquitin ThiolesteraseBombesinGlucagonGlucagon-Like Peptide 1Mixed Function OxygenasesMultienzyme ComplexesPancreatic Polypeptidepancreatic polypeptide, avianPeptide FragmentsPeptide PHIpeptidylglycine monooxygenaseProtein PrecursorsSerotoninThiolester HydrolasesUbiquitin Thiolesterase

Identifiers

PMID10939517
OpenAlexW1601460525

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.