ArticlePlant physiology2000
LEFPS1, a tomato farnesyl pyrophosphate gene highly expressed during early fruit development.
Article in Plant physiology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 55 citations in OpenAlex.
- Biosynthesis of α-Bisabolol by Farnesyl Diphosphate Synthase and α-Bisabolol Synthase and Their Related Transcription Factors inInternational journal of molecular sciences · 2023Article
- Transcriptomic changes induced by applications of a commercial extract of Ascophyllum nodosum on tomato plants.Scientific reports · 2022Article
- Functional analysis ofFrontiers in plant science · 2022Article
- The complete functional characterisation of the terpene synthase family in tomato.The New phytologist · 2020Article
- Agarwood Induction: Current Developments and Future Perspectives.Frontiers in plant science · 2019Review
- Distinct Signatures of Host Defense Suppression by Plant-Feeding Mites.International journal of molecular sciences · 2018Article
- Improved fruit α-tocopherol, carotenoid, squalene and phytosterol contents through manipulation of Brassica juncea 3-HYDROXY-3-METHYLGLUTARYL-COA SYNTHASE1 in transgenic tomato.Plant biotechnology journal · 2018Article
- Article
- Molecular Cloning and Characterisation of Farnesyl Pyrophosphate Synthase from Tripterygium wilfordii.PloS one · 2015Article
- Purification and Characterization of a Novel NAD(P)+-Farnesol Dehydrogenase from Polygonum minus Leaves.PloS one · 2015Article
- Analysis of sea-island cotton and upland cotton in response to Verticillium dahliae infection by RNA sequencing.BMC genomics · 2013Article
- Molecular characterization of farnesyl pyrophosphate synthase from Bacopa monniera by comparative modeling and docking studies.Bioinformation · 2012Article
- Article
- Validation and application of reference genes for quantitative gene expression analyses in various tissues of Bupleurum chinense.Molecular biology reports · 2011Article
- Functional analysis of SlEZ1 a tomato enhancer of zeste (E(z)) gene demonstrates a role in flower development.Plant molecular biology · 2010Article
- Upregulation of phytosterol and triterpene biosynthesis in Centella asiatica hairy roots overexpressed ginseng farnesyl diphosphate synthase.Plant cell reports · 2010Article
- Identification and characterization of genes involved in embryonic crystal cell formation during Drosophila hematopoiesis.Genetics · 2004Article
- Cloning and kinetic characterization of Arabidopsis thaliana solanesyl diphosphate synthase.The Biochemical journal · 2003Article
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7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Farnesyl pyrophosphate synthase (FPS) catalyzes the synthesis of farnesyl pyrophosphate, a key intermediate in sterol and sesquiterpene biosynthesis. Using a polymerase chain reaction-based approach, we have characterized LeFPS1, a tomato (Lycoperscion esculentum cv Wva 106) fruit cDNA, which encodes a functional FPS. We demonstrate that tomato FPSs are encoded by a small multigenic family with genes located on chromosomes 10 and 12. Consistent with farnesyl pyrophosphate requirement in sterol biosynthesis, FPS genes are ubiquitously expressed in tomato plants. Using an LeFPS1 specific probe, we show that the corresponding gene can account for most of FPS mRNA in most plant organs, but not during young seedling development, indicating a differential regulation of FPS genes in tomato. FPS gene expression is also under strict developmental control: FPS mRNA was mainly abundant in young organs and decreased as organs matured with the exception of fruits that presented a biphasic accumulation pattern. In this latter case in situ hybridization studies have shown that FPS mRNA is similarly abundant in all tissues of young fruit. Taken together our results suggest that several FPS isoforms are involved in tomato farnesyl pyrophosphate metabolism and that FPS genes are mostly expressed in relation to cell division and enlargement.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.