Evidence map›Paper›PMID 10934520›Full record

ReviewMolecular biotechnology1999

Reporter gene vectors and assays.

E Schenborn, D Groskreutz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biotechnology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Current Practice in Bicistronic IRES Reporter Use: A Systematic Review.International journal of molecular sciences · 2021
    Pooled it
  2. Pooled it
  3. Review
  4. Article
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  8. Review
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  16. Pre- and postmortem imaging of transplanted cells.International journal of nanomedicine · 2015
    Review
  17. Melittin-glutathione S-transferase fusion protein exhibits anti-inflammatory properties and minimal toxicity.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2014
    Article
  18. Article
  19. Article
  20. Functional anatomy of distant-acting mammalian enhancers.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

E SchenbornPromega Corporation, Madison, WI 53711, USA.
D Groskreutz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene reporter systems play a key role in gene expression and regulation studies. This review describes the ideal reporter systems, including reporter expression vector design. It summarizes the many uses of genetic reporters and outlines the currently available and commonly used reporter systems. Each system is described in terms of the reporter gene, the protein it encodes, and the assays available for detecting presence of the reporter. In addition, each reporter system is analyzed in terms of its recommended uses, advantages, and limitations.

Indexed as

Genes, ReporterGenetic VectorsGene Transfer TechniquesAnimalsBiological AssayGenetic TherapyHumans

Identifiers

PMID10934520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.