ReviewNeoplasia (New York, N.Y.)
Intravital fluorescence videomicroscopy to study tumor angiogenesis and microcirculation.
Review in Neoplasia (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 105 citations in OpenAlex.
- Genetically Engineered Filamentous Bacteriophages Displaying TGF-β1 Promote Angiogenesis in 3D Microenvironments.Journal of functional biomaterials · 2024Article
- Generation of Connective Tissue-Free Microvascular Fragment Isolates from Subcutaneous Fat Tissue of Obese Mice.Tissue engineering and regenerative medicine · 2023Article
- Proof of concept of a multimodal intravital molecular imaging system for tumour transpathology investigation.European journal of nuclear medicine and molecular imaging · 2022Article
- Two-step machine learning method for the rapid analysis of microvascular flow in intravital video microscopy.Scientific reports · 2021Article
- Junctional Adhesion Molecule-C Mediates the Recruitment of Embryonic-Endothelial Progenitor Cells to the Perivascular Niche during Tumor Angiogenesis.International journal of molecular sciences · 2020Article
- Quantitative quality-control metrics forBiomedical optics express · 2019Article
- Deep spectral learning for label-free optical imaging oximetry with uncertainty quantification.Light, science & applications · 2019Article
- Intravital microscopy in the study of the tumor microenvironment: from bench to human application.Oncotarget · 2018Review
- Single capillary oximetry and tissue ultrastructural sensing by dual-band dual-scan inverse spectroscopic optical coherence tomography.Light, science & applications · 2018Article
- In vivo photoacoustic microscopy of human cuticle microvasculature with single-cell resolution.Journal of biomedical optics · 2016Article
- Microvascular quantification based on contour-scanning photoacoustic microscopy.Journal of biomedical optics · 2014Article
- Apoptosis imaging for monitoring DR5 antibody accumulation and pharmacodynamics in brain tumors noninvasively.Cancer research · 2014Article
- Optimization of the dorsal skinfold window chamber model and multi-parametric characterization of tumor-associated vasculature.Intravital · 2014Article
- Multispectral fluorescence ultramicroscopy: three-dimensional visualization and automatic quantification of tumor morphology, drug penetration, and antiangiogenic treatment response.Neoplasia (New York, N.Y.) · 2014Article
- Macromolecule extravasation-xenograft size matters: a systematic study using probe-based confocal laser endomicroscopy (pCLE).Molecular imaging and biology · 2013Article
- Article
- Live cell imaging techniques to study T cell trafficking across the blood-brain barrier in vitro and in vivo.Fluids and barriers of the CNS · 2013Article
- Co-implanting orthotopic tissue creates stroma microenvironment enhancing growth and angiogenesis of multiple tumors.F1000Research · 2013Article
- High interstitial fluid pressure is associated with tumor-line specific vascular abnormalities in human melanoma xenografts.PloS one · 2012Article
- Intravital microscopy evaluation of angiogenesis and its effects on glucose sensor performance.Journal of biomedical materials research. Part A · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Angiogenesis and microcirculation play a central role in growth and metastasis of human neoplasms, and, thus, represent a major target for novel treatment strategies. Mechanistic analysis of processes involved in tumor vascularization, however, requires sophisticated in vivo experimental models and techniques. Intravital microscopy allows direct assessment of tumor angiogenesis, microcirculation and overall perfusion. Its application to the study of tumor-induced neovascularization further provides information on molecular transport and delivery, intra- and extravascular cell-to-cell and cell-to-matrix interaction, as well as tumor oxygenation and metabolism. With the recent advances in the field of bioluminescence and fluorescent reporter genes, appropriate for in vivo imaging, the intravital fluorescent microscopic approach has to be considered a powerful tool to study microvascular, cellular and molecular mechanisms of tumor growth.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.