ArticleThe Journal of cell biology2000
A kinesin-related protein, KRP(180), positions prometaphase spindle poles during early sea urchin embryonic cell division.
Article in The Journal of cell biology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
- Article
- Use of Echinoderm Gametes and Early Embryos for Studying Meiosis and Mitosis.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Unconventional Roles of Cytoskeletal Mitotic Machinery in Neurodevelopment.Trends in cell biology · 2019Review
- Role of Kif15 and its novel mitotic partner KBP in K-fiber dynamics and chromosome alignment.PloS one · 2017Article
- Article
- The crystal structure and biochemical characterization of Kif15: a bifunctional molecular motor involved in bipolar spindle formation and neuronal development.Acta crystallographica. Section D, Biological crystallography · 2014Article
- Phylogenetic analysis of the Kinesin superfamily from physcomitrella.Frontiers in plant science · 2012Article
- Kinesin-12, a mitotic microtubule-associated motor protein, impacts axonal growth, navigation, and branching.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Purification and assay of mitotic motors.Methods (San Diego, Calif.) · 2010Review
- How kinesin motor proteins drive mitotic spindle function: Lessons from molecular assays.Seminars in cell & developmental biology · 2010Review
- Analysis of cytoskeletal and motility proteins in the sea urchin genome assembly.Developmental biology · 2006Article
- The chromokinesin, KLP3A, dives mitotic spindle pole separation during prometaphase and anaphase and facilitates chromatid motility.Molecular biology of the cell · 2004Article
- Identification and phylogenetic analysis of Dictyostelium discoideum kinesin proteins.BMC genomics · 2003Article
- KLP-18, a Klp2 kinesin, is required for assembly of acentrosomal meiotic spindles in Caenorhabditis elegans.Molecular biology of the cell · 2003Article
- subito encodes a kinesin-like protein required for meiotic spindle pole formation in Drosophila melanogaster.Genetics · 2002Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
We have investigated the intracellular roles of an Xklp2-related kinesin motor, KRP(180), in positioning spindle poles during early sea urchin embryonic cell division using quantitative, real-time analysis. Immunolocalization reveals that KRP(180) concentrates on microtubules in the central spindle, but is absent from centrosomes. Microinjection of inhibitory antibodies and dominant negative constructs suggest that KRP(180) is not required for the initial separation of spindle poles, but instead functions to transiently position spindle poles specifically during prometaphase.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.