Evidence map›Paper›PMID 10930434›Full record

ReviewThe Journal of clinical investigation2000

Interactions between insulin resistance and insulin secretion in the development of glucose intolerance.

M K Cavaghan, D A Ehrmann, K S Polonsky

Abstract readReview
In one paragraph

Review in The Journal of clinical investigation, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
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  5. Trial
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  7. Trial
  8. A Novel Blend ofFoods (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Serotonin Influences Insulin Secretion in Rat Insulinoma INS-1E Cells.International journal of molecular sciences · 2024
    Article
  15. Article
  16. Synthesis, In Silico and Kinetics Evaluation ofInternational journal of molecular sciences · 2024
    Article
  17. COVID-19-Induced Diabetes Mellitus: Comprehensive Cellular and Molecular Mechanistic Insights.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Review
  18. Article
  19. Article
  20. Article

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

M K CavaghanDepartment of Medicine, The University of Chicago, Pritzker School of Medicine, Chicago, Illinois, USA.
D A Ehrmann
K S Polonsky

Funding

TRANSGENIC COREP60DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI BELL, GRAEME I · 1985 to 2012
$25.5M
Pilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI Matthew J Brady · 2013 to 2026
$20.9M
ZOLEDRONATE &OSTEOPOROTIC EFFECTS OF ANDROGEN DEPRIVATIM01RR000055 · NCRR · UNIVERSITY OF CHICAGO · PI DE WIT, HARRIET · 1985 to 2007
$19.0M
THE REGULATION OF HEPATIC INSULIN EXTRACTIONR01DK031842 · NIDDK · WASHINGTON UNIVERSITY · PI POLONSKY, KENNETH S · 1986 to 2013
$4.4M
REGULATION OF HEPATIC INSULIN EXTRACTIONR37DK031842 · NIDDK · WASHINGTON UNIVERSITY · PI POLONSKY, KENNETH S · 1997 to 2005
$2.0M
GENETICS OF INSULIN SECRETION AND RESISTANCE IN PCOSK08DK002315 · NIDDK · UNIVERSITY OF CHICAGO · PI EHRMANN, DAVID A · 1995 to 1999
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NCRR NIH HHS M01 RR000055NIDDK NIH HHS DK-02315NIDDK NIH HHS DK-20595NIDDK NIH HHS DK-31842NIDDK NIH HHS P30 DK020595NIDDK NIH HHS P60 DK020595NIDDK NIH HHS R01 DK031842NIDDK NIH HHS R37 DK031842
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsDiabetes Mellitus, Type 2Fatty Acids, NonesterifiedGene ExpressionGlucose IntoleranceHumansInsulinInsulin ResistanceInsulin SecretionIslets of LangerhansMiceFatty Acids, NonesterifiedInsulin

Identifiers

PMID10930434
PMCPMC314336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.