Evidence map›Paper›PMID 10924477›Full record

ArticleGenetics2000

Distinct P-element excision products in somatic and germline cells of Drosophila melanogaster.

G B Gloor, J Moretti, J Mouyal, K J Keeler

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Mosaic Analysis inGenetics · 2018
    Review
  3. Review
  4. Drosophila IRBP bZIP heterodimer binds P-element DNA and affects hybrid dysgenesis.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  5. DNA Transposition at Work.Chemical reviews · 2016
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

G B GloorDepartment of Biochemistry, Faculty of Medicine and Dentistry, The University of Western Ontario, London, Ontario N6A 5C1, Canada. ggloor@julian.uwo.ca
J Moretti
J Mouyal
K J Keeler
Western University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The footprints remaining following somatic P-element excision from the Drosophila white locus were recovered and characterized. Two different types of footprints were observed. Over 75% of the footprints were short, composed of 4 or 7 nucleotides of the P-element inverted terminal repeat, and were similar to those found in a previously described plasmid excision assay. The remaining footprints were composed of 14-18 nucleotides of both inverted terminal repeats. These large footprints were indistinguishable from those recovered following germline P-element excision. Enhanced expression of the Drosophila homologue of the Ku70 protein did not affect the structure of the somatic footprints. Therefore, this protein is not a limiting factor for double-strand break repair by nonhomologous end-joining in Drosophila somatic cells.

Indexed as

Antigens, NuclearDNA HelicasesGerm CellsAnimalsChromatidsCloning, MolecularCrosses, GeneticDNA-Binding ProteinsDNA RepairDNA Transposable ElementsDrosophila melanogasterElectrophoresis, Agar GelExonsGene ConversionIntronsKu AutoantigenAntigens, NuclearDNA-Binding ProteinsDNA HelicasesDNA Transposable ElementsKu AutoantigenNuclear ProteinsRNA, MessengerXRCC5 protein, humanXrcc6 protein, human

Identifiers

PMID10924477
PMCPMC1461202
OpenAlexW2148475410

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.