ArticleApplied and environmental microbiology2000
Extensive polymorphism in Cryptosporidium parvum identified by multilocus microsatellite analysis.
Article in Applied and environmental microbiology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 65 citations in OpenAlex.
- Genetic Diversity of Cryptosporidium in Children in an Urban Informal Settlement of Nairobi, Kenya.PloS one · 2015Trial
- Occurrence and Genetic Diversity ofAnimals : an open access journal from MDPI · 2026Article
- Occurrence and Molecular Characterization ofMicroorganisms · 2025Article
- Review
- Challenges forGenes · 2021Review
- Molecular characterization of Cryptosporidium isolates from high-excreting young dairy calves in dairy cattle herds in Western France.Parasitology research · 2013Article
- Genetic mapping and coccidial parasites: past achievements and future prospects.Journal of biosciences · 2012Review
- Evidence of host-associated populations of Cryptosporidium parvum in Italy.Applied and environmental microbiology · 2012Article
- Multilocus fragment typing and genetic structure of Cryptosporidium parvum Isolates from diarrheic preweaned calves in Spain.Applied and environmental microbiology · 2011Article
- Cases of cryptosporidiosis co-infections in AIDS patients: a correlation between clinical presentation and GP60 subgenotype lineages from aged formalin-fixed stool samples.Annals of tropical medicine and parasitology · 2011Article
- Comparison of single- and multilocus genetic diversity in the protozoan parasites Cryptosporidium parvum and C. hominis.Applied and environmental microbiology · 2010Article
- A hundred-year retrospective on cryptosporidiosis.Trends in parasitology · 2008Review
- Multilocus analysis of Cryptosporidium hominis and Cryptosporidium parvum isolates from sporadic and outbreak-related human cases and C. parvum isolates from sporadic livestock cases in the United Kingdom.Journal of clinical microbiology · 2007Article
- Emergence of distinct genotypes of Cryptosporidium parvum in structured host populations.Applied and environmental microbiology · 2006Article
- Cryptosporidium taxonomy: recent advances and implications for public health.Clinical microbiology reviews · 2004Review
- Electrophoretic analysis of genetic variability within Cryptosporidium parvum from imported and autochthonous cases of human cryptosporidiosis in the United Kingdom.Applied and environmental microbiology · 2003Article
- Molecular epidemiological analysis of Cryptosporidium isolates from humans and animals by using a heteroduplex mobility assay and nucleic acid sequencing based on a small double-stranded RNA element.Journal of clinical microbiology · 2003Article
- Genetic analysis of a Cryptosporidium parvum human genotype 1 isolate passaged through different host species.Infection and immunity · 2002Article
- Analysis of sequence diversity at the highly polymorphic Cpgp40/15 locus among Cryptosporidium isolates from human immunodeficiency virus-infected children in South Africa.Infection and immunity · 2002Article
- Genotyping Cryptosporidium parvum with an hsp70 single-nucleotide polymorphism microarray.Applied and environmental microbiology · 2002Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Restriction fragment length polymorphism and DNA sequence analysis discern two main types of Cryptosporidium parvum. We present a survey of length polymorphism at several microsatellite loci for type 1 and type 2 isolates. A total of 14 microsatellite loci were identified from C. parvum DNA sequences deposited in public databases. All repeats were mono-, di-, and trinucleotide repeats of A, AT, and AAT, reflecting the high AT content of the C. parvum genome. Several of these loci showed significant length polymorphism, with as many as seven alleles identified for a single locus. Differences between alleles ranged from 1 to 27 bp. Karyotype analysis using probes flanking three microsatellites localized each marker to an individual chromosomal band, suggesting that these markers are single copy. In a sample of 19 isolates for which at least three microsatellites were typed, a majority of isolates displayed a unique multilocus fingerprint. Microsatellite analysis of isolates passaged between different host species identified genotypic changes consistent with changes in parasite populations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.