Evidence map›Paper›PMID 10913079›Full record

ArticleJournal of bacteriology2000

Global gene expression profiles of Bacillus subtilis grown under anaerobic conditions.

R W Ye, W Tao, L Bedzyk, T Young, M Chen, L Li

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of bacteriology, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
13.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 208 citations in OpenAlex.

  1. Article
  2. Article
  3. Endobacteria Have a Negative Effect on the Virulence ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Comparison ofNPJ microgravity · 2019
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Heme Synthesis and Acquisition in Bacterial Pathogens.Journal of molecular biology · 2016
    Review
  19. Article
  20. Article

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

R W YeExperimental Station E328/148B, DuPont Central Research and Development, Wilmington, Delaware 19880, USA. rick.ye@usa.dupont.com
W Tao
L Bedzyk
T Young
M Chen
L Li
DuPont (United States) · USExperimental Station · USWilmington University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacillus subtilis can grow under anaerobic conditions, either with nitrate or nitrite as the electron acceptor or by fermentation. A DNA microarray containing 4,020 genes from this organism was constructed to explore anaerobic gene expression patterns on a genomic scale. When mRNA levels of aerobic and anaerobic cultures during exponential growth were compared, several hundred genes were observed to be induced or repressed under anaerobic conditions. These genes are involved in a variety of cell functions, including carbon metabolism, electron transport, iron uptake, antibiotic production, and stress response. Among the highly induced genes are not only those responsible for nitrate respiration and fermentation but also those of unknown function. Certain groups of genes were specifically regulated during anaerobic growth on nitrite, while others were primarily affected during fermentative growth, indicating a complex regulatory circuitry of anaerobic metabolism.

Indexed as

Gene Expression Regulation, BacterialAerobiosisAnaerobiosisBacillus subtilisElectron TransportFermentationGene Expression Regulation, EnzymologicNitratesNitritesOpen Reading FramesPolymerase Chain ReactionRNA, MessengerTranscription, GeneticNitratesNitritesRNA, Messenger

Identifiers

PMID10913079
PMCPMC94617
OpenAlexW2151727574

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.