ArticleNucleic acids research2000
The genes for small nucleolar RNAs in Trypanosoma brucei are organized in clusters and are transcribed as a polycistronic RNA.
Article in Nucleic acids research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Fractional 2'-O-methylation in the ribosomal RNA of Dictyostelium discoideum supports ribosome heterogeneity in Amoebozoa.Scientific reports · 2022Article
- Genome-wide mapping reveals conserved and diverged R-loop activities in the unusual genetic landscape of the African trypanosome genome.Nucleic acids research · 2018Article
- Article
- Cell biology of the trypanosome genome.Microbiology and molecular biology reviews : MMBR · 2010Review
- The transcriptome of the human pathogen Trypanosoma brucei at single-nucleotide resolution.PLoS pathogens · 2010Article
- Psiscan: a computational approach to identify H/ACA-like and AGA-like non-coding RNA in trypanosomatid genomes.BMC bioinformatics · 2008Article
- Elucidating the role of C/D snoRNA in rRNA processing and modification in Trypanosoma brucei.Eukaryotic cell · 2008Article
- A novel class of developmentally regulated noncoding RNAs in Leishmania.Eukaryotic cell · 2006Article
- Genome-wide analyses of two families of snoRNA genes from Drosophila melanogaster, demonstrating the extensive utilization of introns for coding of snoRNAs.RNA (New York, N.Y.) · 2005Article
- A genome-wide analysis of C/D and H/ACA-like small nucleolar RNAs in Trypanosoma brucei reveals a trypanosome-specific pattern of rRNA modification.RNA (New York, N.Y.) · 2005Article
- Pseudouridine-guide RNAs and other Cbf5p-associated RNAs in Euglena gracilis.RNA (New York, N.Y.) · 2004Article
- Novel non-coding RNAs in Dictyostelium discoideum and their expression during development.Nucleic acids research · 2004Article
- Small nucleolar RNA interference induced by antisense or double-stranded RNA in trypanosomatids.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- Life without transcriptional control? From fly to man and back again.The EMBO journal · 2002Review
- Multiple snoRNA gene clusters from Arabidopsis.RNA (New York, N.Y.) · 2001Article
- Identification of 10 novel snoRNA gene clusters from Arabidopsis thaliana.Nucleic acids research · 2001Article
- Small evolutionarily conserved RNA, resembling C/D box small nucleolar RNA, is transcribed from PWCR1, a novel imprinted gene in the Prader-Willi deletion region, which Is highly expressed in brain.American journal of human genetics · 2000Article
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Abstract
Because the organization of snoRNA genes in vertebrates, plants and yeast is diverse, we investigated the organization of snoRNA genes in a distantly related organism, Trypanosoma brucei. We have characterized the second example of a snoRNA gene cluster that is tandemly repeated in the T.BRUCEI: genome. The genes encoding the box C/D snoRNAs TBR12, TBR6, TBR4 and TBR2 make up the cluster. In a genomic organization unique to trypanosomes, there are at least four clusters of these four snoRNA genes tandemly repeated in the T. BRUCEI: genome. We show for the first time that the genes encoding snoRNAs in both this cluster and the SLA cluster are transcribed in an unusual way as a polycistronic RNA.
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