ArticleArchives of disease in childhood2000
Idiopathic pulmonary fibrosis in infants: good prognosis with conservative management.
Article in Archives of disease in childhood, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 28 citations in OpenAlex.
- Review
- A physician survey reveals differences in management of idiopathic pulmonary hemosiderosis.Orphanet journal of rare diseases · 2015Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPulmonary interstitial fibrosis in children is a disease of unknown aetiology, usually associated with a poor prognosis.
methodsIn this case series we describe 11 children presenting over a 10 year period, managed conservatively and associated with a good prognosis.
resultsIn six, symptoms were present from birth and 10 had symptoms at or before 3 months. Diagnosis was made using chest computed tomography and percutaneous lung biopsy. All patients were treated with oral prednisolone. In five no steroid response was noted. One patient responded to hydroxychloroquine. Home oxygen was required in five patients. At follow up all patients are alive at a median age of 6 years (range 1 to 12 years). The two recently diagnosed children have significant symptoms, seven have dyspnoea on exercise, and two are symptom free.
conclusionThe good prognosis seen in these patients is different to previous case reports, indicating a greater than 50% mortality.
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Registered trials
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