ReviewEndocrine-related cancer2000
Tissue architecture and breast cancer: the role of extracellular matrix and steroid hormones.
Review in Endocrine-related cancer, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 0 citations in OpenAlex.
- Spatial Engineering of Mammary Epithelial Cell Cultures with 3D Bioprinting Reveals Growth Control by Branch Point Proximity.Journal of mammary gland biology and neoplasia · 2024Article
- Synthetic MRI in breast cancer: differentiating benign from malignant lesions and predicting immunohistochemical expression status.Scientific reports · 2023Article
- Review
- Context-dependent selection as the keystone in the somatic evolution of cancer.Scientific reports · 2020Article
- A Complex and Evolutive Character: Two Face Aspects of ECM in Tumor Progression.Frontiers in oncology · 2020Review
- Application of the D492 Cell Lines to Explore Breast Morphogenesis, EMT and Cancer Progression in 3D Culture.Journal of mammary gland biology and neoplasia · 2019Review
- 3D culture models for studying branching morphogenesis in the mammary gland and mammalian lung.Biomaterials · 2019Review
- Evaluation of PEG-based hydrogel influence on estrogen receptor driven responses in MCF7 breast cancer cells.ACS biomaterials science & engineering · 2019Article
- MRI texture analysis in differentiating luminal A and luminal B breast cancer molecular subtypes - a feasibility study.BMC medical imaging · 2017Article
- Breast Tissue Metabolism by Magnetic Resonance Spectroscopy.Metabolites · 2017Review
- Is there an association between enhanced choline and β-catenin pathway in breast cancer? A pilot study by MR Spectroscopy and ELISA.Scientific reports · 2017Article
- A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents.Cancer immunology, immunotherapy : CII · 2017Article
- Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays.Nature communications · 2014Article
- Preferential, enhanced breast cancer cell migration on biomimetic electrospun nanofiber 'cell highways'.BMC cancer · 2014Article
- Pregnancy-related characteristics and breast cancer risk.Cancer causes & control : CCC · 2013Article
- Polarity proteins as regulators of cell junction complexes: implications for breast cancer.Pharmacology & therapeutics · 2013Review
- Radial scars and subsequent breast cancer risk: results from the Nurses' Health Studies.Breast cancer research and treatment · 2013Article
- Calcium wave propagation in networks of endothelial cells: model-based theoretical and experimental study.PLoS computational biology · 2012Article
- Mechanistic modeling of the effects of myoferlin on tumor cell invasion.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Organotypic 3D cell culture models: using the rotating wall vessel to study host-pathogen interactions.Nature reviews. Microbiology · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The changes in tissue architecture that accompany the development of breast cancer have been the focus of investigations aimed at developing new cancer therapeutics. As we learn more about the normal mammary gland, we have begun to understand the complex signaling pathways underlying the dramatic shifts in the structure and function of breast tissue. Integrin-, growth factor-, and steroid hormone-signaling pathways all play an important part in maintaining tissue architecture; disruption of the delicate balance of signaling results in dramatic changes in the way cells interact with each other and with the extracellular matrix, leading to breast cancer. The extracellular matrix itself plays a central role in coordinating these signaling processes. In this review, we consider the interrelationships between the extracellular matrix, integrins, growth factors, and steroid hormones in mammary gland development and function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.