ReviewThe Biochemical journal2000
Role of plasma membrane transporters in muscle metabolism.
Review in The Biochemical journal, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 77 citations in OpenAlex.
- The potential causes of myasthenia and fasciculations in severely ill ME/CFS patients: the role of disturbed electrophysiology.Frontiers in physiology · 2025Article
- SSO and other putative inhibitors of FA transport across membranes by CD36 disrupt intracellular metabolism, but do not affect FA translocation.Journal of lipid research · 2020Article
- Amino acid homeostasis and signalling in mammalian cells and organisms.The Biochemical journal · 2017Review
- "Nutraceuticals" in relation to human skeletal muscle and exercise.American journal of physiology. Endocrinology and metabolism · 2017Review
- Article
- D-Amino acid oxidase-induced oxidative stress, 3-bromopyruvate and citrate inhibit angiogenesis, exhibiting potent anticancer effects.Journal of bioenergetics and biomembranes · 2012Article
- 3-Bromopyruvate antagonizes effects of lactate and pyruvate, synergizes with citrate and exerts novel anti-glioma effects.Journal of bioenergetics and biomembranes · 2012Article
- Metabolic Effects of Insulin and IGFs on Gilthead Sea Bream (Sparus aurata) Muscle Cells.Frontiers in endocrinology · 2012Article
- Role of NADH/NAD+ transport activity and glycogen store on skeletal muscle energy metabolism during exercise: in silico studies.American journal of physiology. Cell physiology · 2009Article
- New insights concerning the role of carnitine in the regulation of fuel metabolism in skeletal muscle.The Journal of physiology · 2007Review
- Creatine as a compatible osmolyte in muscle cells exposed to hypertonic stress.The Journal of physiology · 2006Article
- Ketone bodies disturb fatty acid handling in isolated cardiomyocytes derived from control and diabetic rats.The Biochemical journal · 2003Article
- Mouse system-N amino acid transporter, mNAT3, expressed in hepatocytes and regulated by insulin-activated and phosphoinositide 3-kinase-dependent signalling.The Biochemical journal · 2003Article
- Oral creatine supplementation and skeletal muscle metabolism in physical exercise.Sports medicine (Auckland, N.Z.) · 2002Review
- Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance.The Journal of clinical investigation · 2001Article
- Targeting Cancer Cells using 3-bromopyruvate for Selective Cancer Treatment.Saudi journal of medicine & medical sciencesReview
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Muscle plays a major role in metabolism. Thus it is a major glucose-utilizing tissue in the absorptive state, and changes in muscle insulin-stimulated glucose uptake alter whole-body glucose disposal. In some conditions, muscle preferentially uses lipid substrates, such as fatty acids or ketone bodies. Furthermore, muscle is the main reservoir of amino acids and protein. The activity of many different plasma membrane transporters, such as glucose carriers and transporters of carnitine, creatine and amino acids, play a crucial role in muscle metabolism by catalysing the influx or the efflux of substrates across the cell surface. In some cases, the membrane transport process is subjected to intense regulatory control and may become a potential pharmacological target, as is the case with the glucose transporter GLUT4. The goal of this review is the molecular characterization of muscle membrane transporter proteins, as well as the analysis of their possible regulatory role.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.