ArticleInfection and immunity2000
Chlamydia pneumoniae induces inflammatory changes in the heart and aorta of normocholesterolemic C57BL/6J mice.
Article in Infection and immunity, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 71 citations in OpenAlex.
- Biophysical regulation of Chlamydia pneumoniae-infected monocyte recruitment to atherosclerotic foci.Scientific reports · 2016Article
- Article
- Infection and Atherosclerosis Development.Archives of medical research · 2015Review
- Infection with Chlamydia pneumoniae as a cause of coronary heart disease: the hypothesis is still untested.Pathogens and disease · 2015Review
- Periodontal pathogens and atherosclerosis: implications of inflammation and oxidative modification of LDL.BioMed research international · 2014Review
- Shear Stress Enhances Chemokine Secretion fromCellular and molecular bioengineering · 2013Article
- Heat shock protein 10 of Chlamydophila pneumoniae induces proinflammatory cytokines through Toll-like receptor (TLR) 2 and TLR4 in human monocytes THP-1.In vitro cellular & developmental biology. Animal · 2011Article
- Development of diabetes in non-obese diabetic mice promotes Chlamydia pneumoniae dissemination from lung to peripheral blood.International journal of experimental pathology · 2006Article
- Effects of repeated Chlamydia pneumoniae inoculations on aortic lipid accumulation and inflammatory response in C57BL/6J mice.Infection and immunity · 2005Article
- Prevalence and persistence of Chlamydia pneumoniae antibodies in healthy laboratory personnel in Finland.Clinical and diagnostic laboratory immunology · 2005Article
- Age alterations in extent and severity of experimental intranasal infection with Chlamydophila pneumoniae in BALB/c mice.Infection and immunity · 2005Article
- Telithromycin treatment of chronic Chlamydia pneumoniae infection in C57BL/6J mice.Antimicrobial agents and chemotherapy · 2004Article
- Dissemination of Chlamydia pneumoniae to the vessel wall in atherosclerosis.Molecular and cellular biochemistry · 2003Review
- Chlamydia pneumoniae and hyperlipidemia are co-risk factors for atherosclerosis: infection prior to induction of hyperlipidemia does not accelerate development of atherosclerotic lesions in C57BL/6J mice.Infection and immunity · 2002Article
- Chlamydia pneumoniae exacerbates aortic inflammatory foci caused by murine cytomegalovirus infection in normocholesterolemic mice.Clinical and diagnostic laboratory immunology · 2001Article
- Effect of Chlamydia trachomatis infection on atherosclerosis in apolipoprotein E-deficient mice.Infection and immunity · 2000Article
- Potential infectious etiologies of atherosclerosis: a multifactorial perspective.Emerging infectious diseasesReview
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Chlamydia pneumoniae infection induces inflammatory changes in blood vessels in normocholesterolemic rabbits, but it is not known whether the same phenomenon occurs in other animal models. Thus, in this study, C57BL/6J mice were inoculated with C. pneumoniae. Inflammatory changes in the heart or aorta were observed in a small number of chronically infected mice. No evidence of atherosclerotic lesions was found in any of the mice. These findings suggest that chronic C. pneumoniae infection can induce inflammatory changes in the heart and aorta of C57BL/6J mice, but does not initiate definitive atherosclerosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.