ArticleGenome research2000
Eleven densely clustered genes, six of them novel, in 176 kb of mouse t-complex DNA.
Article in Genome research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5.Mammalian genome : official journal of the International Mammalian Genome Society · 2004Article
- Random monoallelic expression of three genes clustered within 60 kb of mouse t complex genomic DNA.Genome research · 2001Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Targeted sequencing of the mouse t-complex has started with a 176-kb, gene-rich BAC localized with six PCR-based markers in inversion 2/3 of the highly duplicated region. The sequence contains 11 genes recovered primarily as cDNAs from early embryonic collections, including Igfals (previously placed on chromosome 17), Nubp2 (a fully characterized gene), Jsap1 (a JNK-binding protein), Rsp29 (the mouse homologue of the rat gene), Ndk3 (a nucleoside diphosphate kinase), and six additional putative genes of unknown function. With 50% GC content, 75% of the DNA transcribed, and one gene/16.0 kb (on average), the region may qualify as one of the most gene-dense segments in the mouse genome and provides candidates for dosage-sensitive phenotypes and mouse embryonic lethals mapped to the vicinity.
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Registered trials
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